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Table 3

Proliferative responses to E75 of PBMCs from vaccinated patients

Patient no.	Prevaccine							Postvaccine
Patient no.		NP	E72	E75	SI (E75)	NP	E72	E75	SI (E75)
1	389 ± 122	280 ± 19	615 ± 168	1.6	nd^a	nd	nd	—
2	295 ± 14	322 ± 46	310 ± 33	1.1	302 ± 70	332 ± 35	890 ± 661	2.9
3	532 ± 202	504 ± 90	793 ± 362	1.5	nd	nd	nd	—
4	nd	nd	nd	—	nd	nd	nd	—
5	309 ± 87	348 ± 121	574 ± 542	1.0	2116 ± 478	1946 ± 731	1685 ± 949	0.8
6	nd	nd	nd	—	663 ± 127	2166 ± 758^b	1281 ± 405^b	1.9
7	2249 ± 1249	2205 ± 897	6089 ± 3351^c	2.5	3262 ± 2678	3951 ± 3000	3751 ± 2191	1.1
8	1758 ± 330	1917 ± 725	4974 ± 1685^c	2.8	585 ± 346	2135 ± 1241	2431 ± 1485^c	4.2
9	864 ± 509	571 ± 230	nd	—	709 ± 437	542 ± 266	536 ± 207	0.8
10	363 ± 189	319 ± 273	1533 ± 667^b	4.2	642 ± 349	402 ± 149	2218 ± 1228^c	3.5
11	457 ± 222	2482 ± 1136^b	5002 ± 508^b	10.9	670 ± 310	1198 ± 713	3149 ± 1032^b	4.7^a
12	468 ± 284	737 ± 795	1550 ± 396^c	3.3	363 ± 190	545 ± 273	726 ± 270	2.0^a
13	nd	nd	nd	—	nd	nd	nd	—
14	nd	nd	nd	—	nd	nd	nd	—

Patient no.	Prevaccine							Postvaccine
Patient no.		NP	E72	E75	SI (E75)	NP	E72	E75	SI (E75)
1	389 ± 122	280 ± 19	615 ± 168	1.6	nd^a	nd	nd	—
2	295 ± 14	322 ± 46	310 ± 33	1.1	302 ± 70	332 ± 35	890 ± 661	2.9
3	532 ± 202	504 ± 90	793 ± 362	1.5	nd	nd	nd	—
4	nd	nd	nd	—	nd	nd	nd	—
5	309 ± 87	348 ± 121	574 ± 542	1.0	2116 ± 478	1946 ± 731	1685 ± 949	0.8
6	nd	nd	nd	—	663 ± 127	2166 ± 758^b	1281 ± 405^b	1.9
7	2249 ± 1249	2205 ± 897	6089 ± 3351^c	2.5	3262 ± 2678	3951 ± 3000	3751 ± 2191	1.1
8	1758 ± 330	1917 ± 725	4974 ± 1685^c	2.8	585 ± 346	2135 ± 1241	2431 ± 1485^c	4.2
9	864 ± 509	571 ± 230	nd	—	709 ± 437	542 ± 266	536 ± 207	0.8
10	363 ± 189	319 ± 273	1533 ± 667^b	4.2	642 ± 349	402 ± 149	2218 ± 1228^c	3.5
11	457 ± 222	2482 ± 1136^b	5002 ± 508^b	10.9	670 ± 310	1198 ± 713	3149 ± 1032^b	4.7^a
12	468 ± 284	737 ± 795	1550 ± 396^c	3.3	363 ± 190	545 ± 273	726 ± 270	2.0^a
13	nd	nd	nd	—	nd	nd	nd	—
14	nd	nd	nd	—	nd	nd	nd	—

^a

Significant decrease from prestimulation (P = 0.04); nd, not done.

^b

Significant at P ≤ 0.001.

^c

Significant at P ≤ 0.05.