Response rates vs. age in Phase 2 studies of 142 patients with CD33 positive AML in first relapse treated with gemtuzumab ozogamicin
Type of remission . | 201/202/203 (n = 142) . | <60 yr (n = 62) . | ≥60 yr (n = 80) . |
---|---|---|---|
CR | |||
No. (%) of patients | 23 (16) | 11/62 (18) | 12/80 (15) |
95% CIsa | (11, 23) | (9, 30) | (8, 25) |
CRp | |||
No. (%) of patients | 19 (13) | 10/62 (16) | 9/80 (11) |
95% CIs | (8, 20) | (8, 28) | (5, 20) |
OR (CR + CRp) | |||
No. (%) of patients | 42 (30) | 21/62 (34) | 21/80 (26) |
95% CIs | (22, 38) | (22, 47) | (17, 37) |
Type of remission . | 201/202/203 (n = 142) . | <60 yr (n = 62) . | ≥60 yr (n = 80) . |
---|---|---|---|
CR | |||
No. (%) of patients | 23 (16) | 11/62 (18) | 12/80 (15) |
95% CIsa | (11, 23) | (9, 30) | (8, 25) |
CRp | |||
No. (%) of patients | 19 (13) | 10/62 (16) | 9/80 (11) |
95% CIs | (8, 20) | (8, 28) | (5, 20) |
OR (CR + CRp) | |||
No. (%) of patients | 42 (30) | 21/62 (34) | 21/80 (26) |
95% CIs | (22, 38) | (22, 47) | (17, 37) |
CI, confidence interval.