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Table 1

Apoptosis and proliferation data (medians) for breast cancer patients

MarkersAll patients (n = 791)LN− (n = 331)LN+ (n = 331)P                  a
Apoptosisb 3.7 3.4 4.1 NSc 
Mitosisd 2.3 1.7 3.1 0.0051 
A:M ratio 1.50 1.56 1.60 NS 
Mitoses/10 HPFs NS 
MIB-1 (%)e 17.8 16.7 19.5 0.0066 
MarkersAll patients (n = 791)LN− (n = 331)LN+ (n = 331)P                  a
Apoptosisb 3.7 3.4 4.1 NSc 
Mitosisd 2.3 1.7 3.1 0.0051 
A:M ratio 1.50 1.56 1.60 NS 
Mitoses/10 HPFs NS 
MIB-1 (%)e 17.8 16.7 19.5 0.0066 
a

Represents value of statistical difference between node-negative and node-positive subsets for each variable.

b

Apoptotic count per 1000.

c

NS, not significant.

d

Mitotic count per 1000.

e

Percentage of cells that are MIB-1-positive.

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