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Table 2

Number of patients displaying the given amounts of GD2+ and tumor cells in the analyzed 106 MNCs

The frequency of GD2+ and GD2+/FISH+ tumor cells in BM samples of 40 NB patients according to the disease stage. The number of samples displaying the respective number of tumor cells/106 MNCs is given.
No. of patients with 1–9No. of patients with 10–99No. of patients with 100–999No. of patients with 1000
No. of patients with 0 GD2+ cellsaGD2+ cellsaTumor cellsbGD2+ cellsaTumor cellsbGD2+ cellsaTumor cellsbGD2+ cellsaTumor cellsb
Stage 1 
Stage 2A, B 
Stage 3 
Stage 4 14 14 
Stage 4s 
No. of patients/total 9/40 12/40 7/40 4/40 4/40 0/40 0/40 15/40 15/40 
The frequency of GD2+ and GD2+/FISH+ tumor cells in BM samples of 40 NB patients according to the disease stage. The number of samples displaying the respective number of tumor cells/106 MNCs is given.
No. of patients with 1–9No. of patients with 10–99No. of patients with 100–999No. of patients with 1000
No. of patients with 0 GD2+ cellsaGD2+ cellsaTumor cellsbGD2+ cellsaTumor cellsbGD2+ cellsaTumor cellsbGD2+ cellsaTumor cellsb
Stage 1 
Stage 2A, B 
Stage 3 
Stage 4 14 14 
Stage 4s 
No. of patients/total 9/40 12/40 7/40 4/40 4/40 0/40 0/40 15/40 15/40 
a

Cells with GD2-specific surface immunofluorescence positivity.

b

Cells positive for both GD2 and tumor typical cytogenetic aberration (FISH).

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