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Table 2

Number of patients displaying the given amounts of GD2⁺ and tumor cells in the analyzed 10⁶ MNCs

The frequency of GD2⁺ and GD2⁺/FISH⁺ tumor cells in BM samples of 40 NB patients according to the disease stage. The number of samples displaying the respective number of tumor cells/10⁶ MNCs is given.
		No. of patients with 1–9			No. of patients with 10–99			No. of patients with 100–999			No. of patients with 1000
		No. of patients with 0 GD2⁺ cells^a	GD2⁺ cells^a	Tumor cells^b	GD2⁺ cells^a	Tumor cells^b	GD2⁺ cells^a	Tumor cells^b	GD2⁺ cells^a	Tumor cells^b
Stage 1	2	1	0	0	0	0	0	0	0
Stage 2A, B	2	1	0	0	0	0	0	0	0
Stage 3	4	3	0	0	0	0	0	0	0
Stage 4	1	4	4	2	2	0	0	14	14
Stage 4s	0	3	3	2	2	0	0	1	1
No. of patients/total	9/40	12/40	7/40	4/40	4/40	0/40	0/40	15/40	15/40

The frequency of GD2⁺ and GD2⁺/FISH⁺ tumor cells in BM samples of 40 NB patients according to the disease stage. The number of samples displaying the respective number of tumor cells/10⁶ MNCs is given.
		No. of patients with 1–9			No. of patients with 10–99			No. of patients with 100–999			No. of patients with 1000
		No. of patients with 0 GD2⁺ cells^a	GD2⁺ cells^a	Tumor cells^b	GD2⁺ cells^a	Tumor cells^b	GD2⁺ cells^a	Tumor cells^b	GD2⁺ cells^a	Tumor cells^b
Stage 1	2	1	0	0	0	0	0	0	0
Stage 2A, B	2	1	0	0	0	0	0	0	0
Stage 3	4	3	0	0	0	0	0	0	0
Stage 4	1	4	4	2	2	0	0	14	14
Stage 4s	0	3	3	2	2	0	0	1	1
No. of patients/total	9/40	12/40	7/40	4/40	4/40	0/40	0/40	15/40	15/40

^a

Cells with GD2-specific surface immunofluorescence positivity.

^b

Cells positive for both GD2 and tumor typical cytogenetic aberration (FISH).