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Table 4

Evaluation of acute peripheral neuropathy symptoms after paclitaxel

Moderate-to-severe symptoms	Without glutamine n = 33 (%)	With glutamine n = 12 (%)	P
Dysesthesias
Fingers	13 (40)	1 (8)	0.047
Toes	14 (42)	1 (8)	0.04
Numbness
Fingers	24 (73)	4 (33)	0.016
Toes	27 (82)	5 (42)	0.009
Paresthesias
Fingers	18 (56)	5 (42)	NS^a
Toes	21 (64)	6 (50)	NS

Moderate-to-severe symptoms	Without glutamine n = 33 (%)	With glutamine n = 12 (%)	P
Dysesthesias
Fingers	13 (40)	1 (8)	0.047
Toes	14 (42)	1 (8)	0.04
Numbness
Fingers	24 (73)	4 (33)	0.016
Toes	27 (82)	5 (42)	0.009
Paresthesias
Fingers	18 (56)	5 (42)	NS^a
Toes	21 (64)	6 (50)	NS

^a

NS, not significant.