Effects of PA and PB on survival of malignant B cells from patients with NHL and CLL
| DX . | Survival (% control) after treatmenta . | . | . | ||
|---|---|---|---|---|---|
| . | PA 5 mm . | PB 1 mm . | PB 2 mm . | ||
| Follicular small cleaved NHL | 76 | 93 | 79 | ||
| Follicular small cleaved NHL | 57 | 53 | 49 | ||
| Follicular small cleaved NHL | 96 | 84 | 58 | ||
| Follicular small cleaved NHL | 82 | 81 | 51 | ||
| Follicular small cleaved NHL | 91 | 78 | 53 | ||
| Follicular small cleaved NHL | 81 | 80 | 24 | ||
| Follicular small cleaved NHL | 66 | 29 | 8 | ||
| Follicular small cleaved NHL | 81 | 74 | 41 | ||
| Follicular mixed NHL | 76 | 60 | 28 | ||
| Diffuse small lymphocytic NHL | 53 | 43 | 54 | ||
| Diffuse small lymphocytic NHL | 69 | 83 | 33 | ||
| Diffuse small lymphocytic NHL | 39 | 35 | 6 | ||
| Diffuse small lymphocytic NHL | 88 | 66 | 19 | ||
| Mantle cell NHL | 55 | 24 | 11 | ||
| Diffuse large cell NHL | 100 | 100 | 75 | ||
| CLL | 72 | 38 | 16 | ||
| CLL | 69 | 50 | 30 | ||
| CLL | 25 | 11 | 3 | ||
| CLL | 45 | 44 | 10 | ||
| CLL | 57 | 43 | 25 | ||
| CLL | 43 | 41 | 21 | ||
| CLL | 40 | 21 | 1 | ||
| CLL | 71 | 51 | 41 | ||
| CLL | 54 | 95 | 29 | ||
| DX . | Survival (% control) after treatmenta . | . | . | ||
|---|---|---|---|---|---|
| . | PA 5 mm . | PB 1 mm . | PB 2 mm . | ||
| Follicular small cleaved NHL | 76 | 93 | 79 | ||
| Follicular small cleaved NHL | 57 | 53 | 49 | ||
| Follicular small cleaved NHL | 96 | 84 | 58 | ||
| Follicular small cleaved NHL | 82 | 81 | 51 | ||
| Follicular small cleaved NHL | 91 | 78 | 53 | ||
| Follicular small cleaved NHL | 81 | 80 | 24 | ||
| Follicular small cleaved NHL | 66 | 29 | 8 | ||
| Follicular small cleaved NHL | 81 | 74 | 41 | ||
| Follicular mixed NHL | 76 | 60 | 28 | ||
| Diffuse small lymphocytic NHL | 53 | 43 | 54 | ||
| Diffuse small lymphocytic NHL | 69 | 83 | 33 | ||
| Diffuse small lymphocytic NHL | 39 | 35 | 6 | ||
| Diffuse small lymphocytic NHL | 88 | 66 | 19 | ||
| Mantle cell NHL | 55 | 24 | 11 | ||
| Diffuse large cell NHL | 100 | 100 | 75 | ||
| CLL | 72 | 38 | 16 | ||
| CLL | 69 | 50 | 30 | ||
| CLL | 25 | 11 | 3 | ||
| CLL | 45 | 44 | 10 | ||
| CLL | 57 | 43 | 25 | ||
| CLL | 43 | 41 | 21 | ||
| CLL | 40 | 21 | 1 | ||
| CLL | 71 | 51 | 41 | ||
| CLL | 54 | 95 | 29 | ||
The percent survival was calculated by MTT assay following a 6-day incubation with diluent (control) or indicated drug.