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Table 2

Effects of PA and PB on survival of malignant B cells from patients with NHL and CLL

DXSurvival (% control) after treatmenta
PA 5 mmPB 1 mmPB 2 mm
Follicular small cleaved NHL 76 93 79 
Follicular small cleaved NHL 57 53 49 
Follicular small cleaved NHL 96 84 58 
Follicular small cleaved NHL 82 81 51 
Follicular small cleaved NHL 91 78 53 
Follicular small cleaved NHL 81 80 24 
Follicular small cleaved NHL 66 29 
Follicular small cleaved NHL 81 74 41 
Follicular mixed NHL 76 60 28 
Diffuse small lymphocytic NHL 53 43 54 
Diffuse small lymphocytic NHL 69 83 33 
Diffuse small lymphocytic NHL 39 35 
Diffuse small lymphocytic NHL 88 66 19 
Mantle cell NHL 55 24 11 
Diffuse large cell NHL 100 100 75 
CLL 72 38 16 
CLL 69 50 30 
CLL 25 11 
CLL 45 44 10 
CLL 57 43 25 
CLL 43 41 21 
CLL 40 21 
CLL 71 51 41 
CLL 54 95 29 
DXSurvival (% control) after treatmenta
PA 5 mmPB 1 mmPB 2 mm
Follicular small cleaved NHL 76 93 79 
Follicular small cleaved NHL 57 53 49 
Follicular small cleaved NHL 96 84 58 
Follicular small cleaved NHL 82 81 51 
Follicular small cleaved NHL 91 78 53 
Follicular small cleaved NHL 81 80 24 
Follicular small cleaved NHL 66 29 
Follicular small cleaved NHL 81 74 41 
Follicular mixed NHL 76 60 28 
Diffuse small lymphocytic NHL 53 43 54 
Diffuse small lymphocytic NHL 69 83 33 
Diffuse small lymphocytic NHL 39 35 
Diffuse small lymphocytic NHL 88 66 19 
Mantle cell NHL 55 24 11 
Diffuse large cell NHL 100 100 75 
CLL 72 38 16 
CLL 69 50 30 
CLL 25 11 
CLL 45 44 10 
CLL 57 43 25 
CLL 43 41 21 
CLL 40 21 
CLL 71 51 41 
CLL 54 95 29 
a

The percent survival was calculated by MTT assay following a 6-day incubation with diluent (control) or indicated drug.

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