Acuracy, sensitivity, specificity, and positive and negative predictive values using hTERT gene expression in the detection of thyroid malignancy
| All calculations were done as follows: (a) accuracy = 100 × [(number of benign without hTERT gene expression) + (number of malignant with hTERT gene expression)]/(total number of cases examined); (b) sensitivity = 100 × (number of malignant with hTERT gene expression)/(number of malignancy); (c) specificity = 100 × (number of benign without hTERT gene expression)/(number of benign); (d) positive predictive value = 100 × (number of malignant with hTERT gene expression)/(number of both benign and malignant with hTERT gene expression); and (e) negative predictive value = 100 × (number of benign without hTERT gene expression)/(number of both benign and malignant with hTERT gene expression). . | . | . | ||
|---|---|---|---|---|
| . | All cases . | Excluding cases with lymphocyte infiltration . | ||
| Accuracy | 74% | 85% | ||
| Sensitivity | 75% | 71% | ||
| Specificity | 72% | 100% | ||
| Negative predictive value | 77% | 77% | ||
| Positive predictive value | 71% | 100% | ||
| All calculations were done as follows: (a) accuracy = 100 × [(number of benign without hTERT gene expression) + (number of malignant with hTERT gene expression)]/(total number of cases examined); (b) sensitivity = 100 × (number of malignant with hTERT gene expression)/(number of malignancy); (c) specificity = 100 × (number of benign without hTERT gene expression)/(number of benign); (d) positive predictive value = 100 × (number of malignant with hTERT gene expression)/(number of both benign and malignant with hTERT gene expression); and (e) negative predictive value = 100 × (number of benign without hTERT gene expression)/(number of both benign and malignant with hTERT gene expression). . | . | . | ||
|---|---|---|---|---|
| . | All cases . | Excluding cases with lymphocyte infiltration . | ||
| Accuracy | 74% | 85% | ||
| Sensitivity | 75% | 71% | ||
| Specificity | 72% | 100% | ||
| Negative predictive value | 77% | 77% | ||
| Positive predictive value | 71% | 100% | ||