Characteristics of the tumors according to high (groups B and D) or low (groups A and C) vessel density
| . | Groups B and D . | Groups A and C . | P . | |||
|---|---|---|---|---|---|---|
| Vessel density | 17.1 ± 11.0 | 3.1 ± 1.7 | <0.0001 | |||
| PCNA index (%) | 28.1 ± 18.5 | 21.9 ± 16.0 | 0.07 | |||
| Apoptosis | 0.44 ± 0.34 | 0.29 ± 0.24 | 0.01 | |||
| VEGF | ||||||
| Positive | 27 (67%) | 24 (51%) | 0.12 | |||
| Negative | 13 | 23 | ||||
| bFGF | ||||||
| Positive | 27 (73%) | 27 (63%) | 0.33 | |||
| Negative | 10 | 16 | ||||
| PDGF | ||||||
| Positive | 18 (51%) | 24 (57%) | 0.61 | |||
| Negative | 17 | 18 | ||||
| Growth in mice | ||||||
| Yes | f7 (27%) | 20 (57%) | 0.01 | |||
| No | 19 | 15 | ||||
| Metastasisa | ||||||
| Positive | 27 (67%) | 28 (61%) | 0.52 | |||
| Negative | 13 | 18 | ||||
| Survival (weeks) | 111 | 64 | 0.20 | |||
| . | Groups B and D . | Groups A and C . | P . | |||
|---|---|---|---|---|---|---|
| Vessel density | 17.1 ± 11.0 | 3.1 ± 1.7 | <0.0001 | |||
| PCNA index (%) | 28.1 ± 18.5 | 21.9 ± 16.0 | 0.07 | |||
| Apoptosis | 0.44 ± 0.34 | 0.29 ± 0.24 | 0.01 | |||
| VEGF | ||||||
| Positive | 27 (67%) | 24 (51%) | 0.12 | |||
| Negative | 13 | 23 | ||||
| bFGF | ||||||
| Positive | 27 (73%) | 27 (63%) | 0.33 | |||
| Negative | 10 | 16 | ||||
| PDGF | ||||||
| Positive | 18 (51%) | 24 (57%) | 0.61 | |||
| Negative | 17 | 18 | ||||
| Growth in mice | ||||||
| Yes | f7 (27%) | 20 (57%) | 0.01 | |||
| No | 19 | 15 | ||||
| Metastasisa | ||||||
| Positive | 27 (67%) | 28 (61%) | 0.52 | |||
| Negative | 13 | 18 | ||||
| Survival (weeks) | 111 | 64 | 0.20 | |||
One case could not be defined.