Clinical features and clonal relationships of paired tumors
| . | . | ESCC . | . | . | |
|---|---|---|---|---|---|
| Patient no. . | HNSCC Site . | Intervala . | Location in esophagusb . | Clonal relationship (by molecular analysis) . | |
| 1 | Hypopharynx | 0 | Lower | Not clonal | |
| 2 | Hypopharynx | 0 | Lower | Not clonal | |
| 3 | Hypopharynx | 14 | Upper | Not clonal | |
| 4 | Glottic larynx | 0 | Middle | Not clonal | |
| 5 | Hypopharynx | 16 | Upper | Clonal | |
| 6 | Floor of mouth | 0 | Middle | Not clonal | |
| 7 | Supraglottic larynx | 0 | Middle | Not clonal | |
| 8 | Base of tongue | 14 | Upper | Not clonal | |
| 9 | Tonsil | 0 | Lower | Clonal | |
| 10 | Glottic larynx | 49 | Middle | Not clonal | |
| 11 | Hypopharynx | 0 | Lower | Not clonal | |
| 12 | Floor of mouth | 0 | Middle | Not clonal | |
| 13 | Base of tongue | 0 | Upper | Not clonal | |
| 14 | Tonsil | 0 | Middle | Not clonal | |
| 15 | Hypopharynx | 0 | Middle | Not clonal | |
| 16 | Lateral tongue | 0 | Upper | Not clonal | |
| . | . | ESCC . | . | . | |
|---|---|---|---|---|---|
| Patient no. . | HNSCC Site . | Intervala . | Location in esophagusb . | Clonal relationship (by molecular analysis) . | |
| 1 | Hypopharynx | 0 | Lower | Not clonal | |
| 2 | Hypopharynx | 0 | Lower | Not clonal | |
| 3 | Hypopharynx | 14 | Upper | Not clonal | |
| 4 | Glottic larynx | 0 | Middle | Not clonal | |
| 5 | Hypopharynx | 16 | Upper | Clonal | |
| 6 | Floor of mouth | 0 | Middle | Not clonal | |
| 7 | Supraglottic larynx | 0 | Middle | Not clonal | |
| 8 | Base of tongue | 14 | Upper | Not clonal | |
| 9 | Tonsil | 0 | Lower | Clonal | |
| 10 | Glottic larynx | 49 | Middle | Not clonal | |
| 11 | Hypopharynx | 0 | Lower | Not clonal | |
| 12 | Floor of mouth | 0 | Middle | Not clonal | |
| 13 | Base of tongue | 0 | Upper | Not clonal | |
| 14 | Tonsil | 0 | Middle | Not clonal | |
| 15 | Hypopharynx | 0 | Middle | Not clonal | |
| 16 | Lateral tongue | 0 | Upper | Not clonal | |
Months between treatment of head and neck cancer and diagnosis of esophageal cancer; an interval of 0 months indicates diagnosis was made during the evaluation of head and neck cancer.
Upper, cervical portion extending approximately 18 cm from the upper incisor teeth; Middle, upper thoracic portion extending from the thoracic inlet to the level of the tracheal bifurcation; Lower, lower thoracic portion from the level of the tracheal bifurcation to the esophagogastric junction.