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Table 2.

Stage categorized by PSMA-PET PROMISE criteria (16)

miTNM stage, n (%)All patients (N = 200)PSADT of ≤10 months (n = 115)Gleason score of ≥8 only (n = 85)
M0 91 (46) 48 (42) 43 (51) 
 T0N0M0 4 (2) 4 (3) 0 (0) 
 TrN0M0 48 (24) 22 (19) 26 (31) 
 T0N1M0 13 (7) 11 (10) 2 (2) 
 TrN1M0 26 (13) 11 (10) 15 (18) 
M1 109 (55) 67 (58) 42 (49) 
 T0N0M1 31 (16) 15 (13) 16 (19) 
 TrN0M1 9 (5) 6 (5) 3 (4) 
 T0N1M1 42 (21) 30 (26) 12 (14) 
 TrN1M1 27 (14) 16 (14) 11 (13) 
Extrapelvic diseasea    
 M1a (lymph node) 77 (39) 51 (44) 26 (31) 
 M1b (bone) 47 (24) 26 (23) 21 (25) 
 M1cb (visceral) 12b (6) 8 (7) 4 (5) 
N/M disease extent    
 Unifocal (1) 29 (15) 19 (17) 10 (12) 
 Oligometastatic (2–3) 28 (14) 16 (14) 12 (14) 
 Multiple/disseminated (≥4) 91 (46) 54 (47) 37 (44) 
miTNM stage, n (%)All patients (N = 200)PSADT of ≤10 months (n = 115)Gleason score of ≥8 only (n = 85)
M0 91 (46) 48 (42) 43 (51) 
 T0N0M0 4 (2) 4 (3) 0 (0) 
 TrN0M0 48 (24) 22 (19) 26 (31) 
 T0N1M0 13 (7) 11 (10) 2 (2) 
 TrN1M0 26 (13) 11 (10) 15 (18) 
M1 109 (55) 67 (58) 42 (49) 
 T0N0M1 31 (16) 15 (13) 16 (19) 
 TrN0M1 9 (5) 6 (5) 3 (4) 
 T0N1M1 42 (21) 30 (26) 12 (14) 
 TrN1M1 27 (14) 16 (14) 11 (13) 
Extrapelvic diseasea    
 M1a (lymph node) 77 (39) 51 (44) 26 (31) 
 M1b (bone) 47 (24) 26 (23) 21 (25) 
 M1cb (visceral) 12b (6) 8 (7) 4 (5) 
N/M disease extent    
 Unifocal (1) 29 (15) 19 (17) 10 (12) 
 Oligometastatic (2–3) 28 (14) 16 (14) 12 (14) 
 Multiple/disseminated (≥4) 91 (46) 54 (47) 37 (44) 

NOTE: Numbers in boldface represent the total.

Abbreviations: miTNM, molecular imaging TNM; TNM, tumor, nodes,

metastases; Tr, local recurrence in the prostate bed.

aPROMISE allows patients to be counted under multiple M1 categories.

bLung (n = 4), liver (n = 5), peritoneum (n = 4), and connective tissue (n = 1) with overlap.

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