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Table 1.

Radiobiological variables from surviving curves

Mean inactivation doseEnhancement ratioSurvival fraction (2 Gy)Gy (1%)
Control 3.66  0.70 10.83 
SH-123 (20 μmol/L) 2.96 1.24 0.57 10.49 
SH-130 (5 μmol/L) 2.53 1.45 0.49 9.53 
SH-130 (10 μmol/L) 2.05 1.79 0.40 8.42 
SH-130 (20 μmol/L) 1.28 2.86 0.21 5.63 
Mean inactivation doseEnhancement ratioSurvival fraction (2 Gy)Gy (1%)
Control 3.66  0.70 10.83 
SH-123 (20 μmol/L) 2.96 1.24 0.57 10.49 
SH-130 (5 μmol/L) 2.53 1.45 0.49 9.53 
SH-130 (10 μmol/L) 2.05 1.79 0.40 8.42 
SH-130 (20 μmol/L) 1.28 2.86 0.21 5.63 

NOTE: Radiobiological variables were calculated from survival curves in Fig. 1C based on linear-quadratic model. Enhancement ratio was calculated from mean inactivation dose in control group divided by that in treated group. Gy (1%), radiation dose leading to 1% cell survival.

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