Radiobiological variables from surviving curves
. | Mean inactivation dose . | Enhancement ratio . | Survival fraction (2 Gy) . | Gy (1%) . |
---|---|---|---|---|
Control | 3.66 | 0.70 | 10.83 | |
SH-123 (20 μmol/L) | 2.96 | 1.24 | 0.57 | 10.49 |
SH-130 (5 μmol/L) | 2.53 | 1.45 | 0.49 | 9.53 |
SH-130 (10 μmol/L) | 2.05 | 1.79 | 0.40 | 8.42 |
SH-130 (20 μmol/L) | 1.28 | 2.86 | 0.21 | 5.63 |
. | Mean inactivation dose . | Enhancement ratio . | Survival fraction (2 Gy) . | Gy (1%) . |
---|---|---|---|---|
Control | 3.66 | 0.70 | 10.83 | |
SH-123 (20 μmol/L) | 2.96 | 1.24 | 0.57 | 10.49 |
SH-130 (5 μmol/L) | 2.53 | 1.45 | 0.49 | 9.53 |
SH-130 (10 μmol/L) | 2.05 | 1.79 | 0.40 | 8.42 |
SH-130 (20 μmol/L) | 1.28 | 2.86 | 0.21 | 5.63 |
NOTE: Radiobiological variables were calculated from survival curves in Fig. 1C based on linear-quadratic model. Enhancement ratio was calculated from mean inactivation dose in control group divided by that in treated group. Gy (1%), radiation dose leading to 1% cell survival.