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Table 4.

Cox multivariate analysis of disease-free survival in ER-positive breast cancer

VariableHR (95% CI)P*
Lymph node status 4.047 (2.137-7.663) <0.0005 
P-S167 0.506 (0.313-0.819) 0.006 
HER2 1.833 (1.145-2.935) 0.012 
VariableHR (95% CI)P*
Lymph node status 4.047 (2.137-7.663) <0.0005 
P-S167 0.506 (0.313-0.819) 0.006 
HER2 1.833 (1.145-2.935) 0.012 

NOTE: Multivariate analysis was done using stepwise Cox proportional hazards regression with forward selection. Candidate exploratory variables included age, tumor size, tumor grade, lymph nodes, ER, PR, HER2, P-MAPK, P-AKT, P-p90RSK, P-S118, and P-S167.

Abbreviations: HR, hazard ratio; 95% CI, 95% confidence interval.

*

Two-sided Wald test was used.

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