Characteristics of ER-positive breast cancer patients (n = 290) and their primary tumors
| . | No. patients (%) . | |
|---|---|---|
| Age (y) | ||
| <50 | 74 (25) | |
| ≥50 | 216 (75) | |
| Tumor size (cm) | ||
| <2 | 109 (38) | |
| 2-5 | 134 (46) | |
| >5 | 26 (9) | |
| Unknown | 21 (7) | |
| Histologic grade | ||
| 1 | 40 (14) | |
| 2 | 176 (61) | |
| 3 | 62 (21) | |
| Unknown | 11 (4) | |
| Lymph node status | ||
| Negative | 87 (30) | |
| Positive | 139 (48) | |
| Unknown | 64 (22) | |
| PR | ||
| Negative | 83 (29) | |
| Positive | 207 (71) | |
| HER2/c-erbB2 | ||
| Negative | 225 (77) | |
| Positive | 57 (20) | |
| Not determined | 8 (3) | |
| P-MAPK (Thr202/Tyr204) | ||
| Negative | 90 (31) | |
| Positive | 200 (69) | |
| P-AKT (Ser473) | ||
| Negative | 84 (29) | |
| Positive | 190 (66) | |
| Not determined | 16 (5) | |
| P-p90RSK (Thr359/Ser363) | ||
| Negative | 40 (14) | |
| Positive | 234 (81) | |
| Not determined | 16 (5) | |
| P-S118 | ||
| Negative | 50 (17) | |
| Positive | 240 (77) | |
| P-S167 | ||
| Negative | 56 (19) | |
| Positive | 229 (79) | |
| Not determined | 5 (2) | |
| . | No. patients (%) . | |
|---|---|---|
| Age (y) | ||
| <50 | 74 (25) | |
| ≥50 | 216 (75) | |
| Tumor size (cm) | ||
| <2 | 109 (38) | |
| 2-5 | 134 (46) | |
| >5 | 26 (9) | |
| Unknown | 21 (7) | |
| Histologic grade | ||
| 1 | 40 (14) | |
| 2 | 176 (61) | |
| 3 | 62 (21) | |
| Unknown | 11 (4) | |
| Lymph node status | ||
| Negative | 87 (30) | |
| Positive | 139 (48) | |
| Unknown | 64 (22) | |
| PR | ||
| Negative | 83 (29) | |
| Positive | 207 (71) | |
| HER2/c-erbB2 | ||
| Negative | 225 (77) | |
| Positive | 57 (20) | |
| Not determined | 8 (3) | |
| P-MAPK (Thr202/Tyr204) | ||
| Negative | 90 (31) | |
| Positive | 200 (69) | |
| P-AKT (Ser473) | ||
| Negative | 84 (29) | |
| Positive | 190 (66) | |
| Not determined | 16 (5) | |
| P-p90RSK (Thr359/Ser363) | ||
| Negative | 40 (14) | |
| Positive | 234 (81) | |
| Not determined | 16 (5) | |
| P-S118 | ||
| Negative | 50 (17) | |
| Positive | 240 (77) | |
| P-S167 | ||
| Negative | 56 (19) | |
| Positive | 229 (79) | |
| Not determined | 5 (2) | |