Association of histopathologic variables and number of aberrations with the cluster groups identified by the unsupervised hierarchical cluster analysis
. | Group I (n = 11) . | Group II (n = 15)* . | Group III (n = 14)* . | P . | ||||
---|---|---|---|---|---|---|---|---|
Histology | ||||||||
ILC | 2 | 10 | 9 | 0.02 | ||||
IDC | 9 | 5 | 4 | |||||
ER | ||||||||
Positive | 6 | 13 | 14 | 0.005 | ||||
Negative | 5 | 1 | 0 | |||||
Grading | ||||||||
1 | 1 | 1 | — | 0.004 | ||||
2 | 2 | 11 | 6 | |||||
3 | 8 | 3 | 8 | |||||
Aberrations | 10.2% | 11.3% | 21.3% | <0.001 | ||||
Gains | 7.9% | 5.1% | 10.7% | <0.001 | ||||
Losses | 2.3% | 6.2% | 10.6% | <0.001 |
. | Group I (n = 11) . | Group II (n = 15)* . | Group III (n = 14)* . | P . | ||||
---|---|---|---|---|---|---|---|---|
Histology | ||||||||
ILC | 2 | 10 | 9 | 0.02 | ||||
IDC | 9 | 5 | 4 | |||||
ER | ||||||||
Positive | 6 | 13 | 14 | 0.005 | ||||
Negative | 5 | 1 | 0 | |||||
Grading | ||||||||
1 | 1 | 1 | — | 0.004 | ||||
2 | 2 | 11 | 6 | |||||
3 | 8 | 3 | 8 | |||||
Aberrations | 10.2% | 11.3% | 21.3% | <0.001 | ||||
Gains | 7.9% | 5.1% | 10.7% | <0.001 | ||||
Losses | 2.3% | 6.2% | 10.6% | <0.001 |
Group II contains tumor ILC.341 with unknown ER and Her2neu status, and tumor IDC.327 with unknown Her2neu status. Group III contains tumor 350, which exhibits both histologies.