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Table 3

Multivariate Cox regression analysis of potential risk factors for tumor relapse in patients with R0 resected NSCLC

RR95% Confidence intervalP
Sex Male 0.77 0.28-2.10 0.61 
 Female    
Age (y) ≤65 0.75 0.36-1.56 0.44 
 >65    
Histology Squamous cell carcinoma 1.77 0.77-4.05 0.17 
 Adenocarcinoma    
Tumor-node-metastasis stage   0.23 
 II 0.79 0.28-2.25 0.67 
 III 1.82 0.76-4.36 0.17 
Grading well/moderately well differentiated 0.85 0.35-2.06 0.73 
 poorly differentiated/undifferentiated    
MMP-12 Low expression 4.86 1.06-22.26 0.04 
 High expression    
RR95% Confidence intervalP
Sex Male 0.77 0.28-2.10 0.61 
 Female    
Age (y) ≤65 0.75 0.36-1.56 0.44 
 >65    
Histology Squamous cell carcinoma 1.77 0.77-4.05 0.17 
 Adenocarcinoma    
Tumor-node-metastasis stage   0.23 
 II 0.79 0.28-2.25 0.67 
 III 1.82 0.76-4.36 0.17 
Grading well/moderately well differentiated 0.85 0.35-2.06 0.73 
 poorly differentiated/undifferentiated    
MMP-12 Low expression 4.86 1.06-22.26 0.04 
 High expression    
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