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Table 3.

Multivariate Cox analysis of overall survival of 90 patients with NSCLC

FactorβSEχ2PHazard ratio (95% confidence interval)
APN/CD13      
    ≤6.5 1.418 0.388 13.361 <0.001 4.1 (1.9-8.8) 
    >6.5      
Age (y)      
    ≤70 −0.122 0.346 0.125 0.724 0.9 (0.4-1.7) 
    >70      
Sex      
    Female −0.055 0.341 0.026 0.871 0.9 (0.5-1.8) 
    Male      
Performance status      
    0-2 1.227 0.434 7.994 0.005 3.4 (1.5-8.0) 
    3, 4      
Stage      
    I-IIIA 2.154 0.551 15.277 <0.001 8.6 (3.0-25.4) 
    IIIB, IV      
Histology      
    Nonadenocarcinoma −0.514 0.386 1.767 0.183 0.6 (0.3-1.3) 
    Adenocarcinoma      
Serum CEA      
    Normal 0.054 0.331 0.026 0.872 1.1 (0.6-2.0) 
    More than normal      
FactorβSEχ2PHazard ratio (95% confidence interval)
APN/CD13      
    ≤6.5 1.418 0.388 13.361 <0.001 4.1 (1.9-8.8) 
    >6.5      
Age (y)      
    ≤70 −0.122 0.346 0.125 0.724 0.9 (0.4-1.7) 
    >70      
Sex      
    Female −0.055 0.341 0.026 0.871 0.9 (0.5-1.8) 
    Male      
Performance status      
    0-2 1.227 0.434 7.994 0.005 3.4 (1.5-8.0) 
    3, 4      
Stage      
    I-IIIA 2.154 0.551 15.277 <0.001 8.6 (3.0-25.4) 
    IIIB, IV      
Histology      
    Nonadenocarcinoma −0.514 0.386 1.767 0.183 0.6 (0.3-1.3) 
    Adenocarcinoma      
Serum CEA      
    Normal 0.054 0.331 0.026 0.872 1.1 (0.6-2.0) 
    More than normal      

Abbreviations: APN, aminopeptidase N; CEA, carcinoembryonic antigen.

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