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Table 5.

Amounts of total catechin (mg) recovered in the urine over 24 hours after oral administration of Polyphenon E in the absence or presence of food

CatechinPolyphenon E (400 mg epigallocatechin gallate)
Polyphenon E (800 mg epigallocatechin gallate)
Polyphenon E (1,200 mg epigallocatechin gallate)
FedFastingFedFastingFedFasting
Epigallocatechin 4.85 ± 1.83* 2.67 ± 1.25 5.54 ± 1.59 4.49 ± 3.15 6.48 ± 4.10 5.39 ± 3.09 
Epicatechin 4.62 ± 1.76 2.64 ± 1.13 6.49 ± 2.28 5.26 ± 3.54 9.20 ± 6.25 6.44 ± 4.11 
CatechinPolyphenon E (400 mg epigallocatechin gallate)
Polyphenon E (800 mg epigallocatechin gallate)
Polyphenon E (1,200 mg epigallocatechin gallate)
FedFastingFedFastingFedFasting
Epigallocatechin 4.85 ± 1.83* 2.67 ± 1.25 5.54 ± 1.59 4.49 ± 3.15 6.48 ± 4.10 5.39 ± 3.09 
Epicatechin 4.62 ± 1.76 2.64 ± 1.13 6.49 ± 2.28 5.26 ± 3.54 9.20 ± 6.25 6.44 ± 4.11 
*

Mean ± 1 SD.

Significantly different from the fed condition, P < 0.005 when data were pooled from all doses.

Significantly different from the fed condition, P < 0.0005 when data were pooled from all doses.

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