American Association for Cancer Research

Table 5.

Amounts of total catechin (mg) recovered in the urine over 24 hours after oral administration of Polyphenon E in the absence or presence of food

Catechin	Polyphenon E (400 mg epigallocatechin gallate)			Polyphenon E (800 mg epigallocatechin gallate)
	Fed	Fasting	Fed	Fasting	Fed	Fasting
Epigallocatechin	4.85 ± 1.83*	2.67 ± 1.25^†	5.54 ± 1.59	4.49 ± 3.15^†	6.48 ± 4.10	5.39 ± 3.09^†
Epicatechin	4.62 ± 1.76	2.64 ± 1.13^‡	6.49 ± 2.28	5.26 ± 3.54^‡	9.20 ± 6.25	6.44 ± 4.11^‡

Catechin	Polyphenon E (400 mg epigallocatechin gallate)			Polyphenon E (800 mg epigallocatechin gallate)
	Fed	Fasting	Fed	Fasting	Fed	Fasting
Epigallocatechin	4.85 ± 1.83*	2.67 ± 1.25^†	5.54 ± 1.59	4.49 ± 3.15^†	6.48 ± 4.10	5.39 ± 3.09^†
Epicatechin	4.62 ± 1.76	2.64 ± 1.13^‡	6.49 ± 2.28	5.26 ± 3.54^‡	9.20 ± 6.25	6.44 ± 4.11^‡

Mean ± 1 SD.

Significantly different from the fed condition, P < 0.005 when data were pooled from all doses.

Significantly different from the fed condition, P < 0.0005 when data were pooled from all doses.