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Table 3.

A comparison of interpatient and intrapatient variability in PET parameters of 2-[11C]thymidine retention in different tissues

ParameterTissue (n)Mean ± SDCOV (%)
InterpatientIntrapatient
SUVend Tumor (45) 2.00 ± 0.80 38 8* 
 Liver (26) 1.90 ± 0.85 45 13 
 Spleen (22) 1.40 ± 0.17 40 13 
AUC0-1 hour Tumor (45) 155 ± 49 32 2* 
 Liver (26) 157 ± 33 21 8 
 Spleen (22) 119 ± 5 5 
FRT Tumor (36) 0.30 ± 0.14 47 9 
 Liver (26) 0.23 ± 0.08 35 4 
 Spleen (22) 0.15 ± 0.03 20 24§ 
ParameterTissue (n)Mean ± SDCOV (%)
InterpatientIntrapatient
SUVend Tumor (45) 2.00 ± 0.80 38 8* 
 Liver (26) 1.90 ± 0.85 45 13 
 Spleen (22) 1.40 ± 0.17 40 13 
AUC0-1 hour Tumor (45) 155 ± 49 32 2* 
 Liver (26) 157 ± 33 21 8 
 Spleen (22) 119 ± 5 5 
FRT Tumor (36) 0.30 ± 0.14 47 9 
 Liver (26) 0.23 ± 0.08 35 4 
 Spleen (22) 0.15 ± 0.03 20 24§ 

NOTE: n, total number of patients scanned. Data are missing because of an inadequate volume of normal tissue within the PET image or because an input function could not be obtained (FRT).

*

Seven patients were scanned for the assessment of intrapatient COV.

n = 6.

n = 4.

§

n = 5.

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