American Association for Cancer Research

Table 3.

A comparison of interpatient and intrapatient variability in PET parameters of 2-[¹¹C]thymidine retention in different tissues

Parameter	Tissue (n)	Mean ± SD	COV (%)
Parameter	Tissue (n)	Mean ± SD				Interpatient	Intrapatient
SUV_end	Tumor (45)	2.00 ± 0.80	38	8*
		Liver (26)	1.90 ± 0.85	45	13^†
		Spleen (22)	1.40 ± 0.17	40	13^†
AUC_{0-1 hour}	Tumor (45)	155 ± 49	32	2*
		Liver (26)	157 ± 33	21	8^†
		Spleen (22)	119 ± 5	4	5^†
FRT	Tumor (36)	0.30 ± 0.14	47	9^†
		Liver (26)	0.23 ± 0.08	35	4^‡
		Spleen (22)	0.15 ± 0.03	20	24^§

Parameter	Tissue (n)	Mean ± SD	COV (%)
Parameter	Tissue (n)	Mean ± SD				Interpatient	Intrapatient
SUV_end	Tumor (45)	2.00 ± 0.80	38	8*
		Liver (26)	1.90 ± 0.85	45	13^†
		Spleen (22)	1.40 ± 0.17	40	13^†
AUC_{0-1 hour}	Tumor (45)	155 ± 49	32	2*
		Liver (26)	157 ± 33	21	8^†
		Spleen (22)	119 ± 5	4	5^†
FRT	Tumor (36)	0.30 ± 0.14	47	9^†
		Liver (26)	0.23 ± 0.08	35	4^‡
		Spleen (22)	0.15 ± 0.03	20	24^§

NOTE: n, total number of patients scanned. Data are missing because of an inadequate volume of normal tissue within the PET image or because an input function could not be obtained (FRT).

Seven patients were scanned for the assessment of intrapatient COV.

†

n = 6.

‡

n = 4.

n = 5.

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