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Table 3

Hematologic toxicities^a

Dose level	No. of patients/cycles	Anemia							Neutropenia							Thrombocytopenia
Dose level	No. of patients/cycles			G1	G2	G3	G4	G1	G2	G3	G4	G1	G2	G3	G4
1	3/24	0	0	0	0	2	0	0	0	1	0	0	0
2	3/15	0	0	0	0	0	0	0	0	0	0	0	0
3	6/16	1	5	0	0	1	0	2	0	0	0	0	0
4	6/16	9	1	0	0	0	1	3	0	0	0	0	0
5	3/10	0	0	0	0	0	0	0	1	0	0	0	0

Dose level	No. of patients/cycles	Anemia							Neutropenia							Thrombocytopenia
Dose level	No. of patients/cycles			G1	G2	G3	G4	G1	G2	G3	G4	G1	G2	G3	G4
1	3/24	0	0	0	0	2	0	0	0	1	0	0	0
2	3/15	0	0	0	0	0	0	0	0	0	0	0	0
3	6/16	1	5	0	0	1	0	2	0	0	0	0	0
4	6/16	9	1	0	0	0	1	3	0	0	0	0	0
5	3/10	0	0	0	0	0	0	0	1	0	0	0	0

^a

Expressed as the number of cycles with indicated side effects during the treatments.