ORs for the association of vasectomy with risk of prostate cancer according to clinical characteristics of cancer patients, King County, Washington, 1993–1996
| Characteristic . | Vasectomy status . | . | ORa . | 95% CI . | |
|---|---|---|---|---|---|
| . | No (n = 456) . | Yes (n = 297) . | . | . | |
| Stage at diagnosis | |||||
| A | 66 (14.5)b | 48 (16.2) | 1.19 | 0.8 –1.8 | |
| B | 262 (57.5) | 177 (59.6) | 1.16 | 0.9 –1.5 | |
| C | 77 (16.9) | 47 (15.8) | 1.04 | 0.7 –1.6 | |
| D | 39 (8.6) | 18 (6.1) | 0.78 | 0.4 –1.4 | |
| Unk | 12 (2.6) | 7 (2.4) | |||
| Gleason grade | |||||
| 2–4 | 51 (11.2) | 35 (11.8) | 1.23 | 0.8 –2.0 | |
| 5–7 | 318 (69.7) | 228 (76.8) | 1.22 | 0.9 –1.6 | |
| 8–10 | 80 (17.5) | 31 (10.4) | 0.66 | 0.4 –1.0 | |
| Unk | 7 (1.5) | 3 (1.0) | |||
| Symptomsc at diagnosis | |||||
| No | 297 (65.1) | 206 (69.4) | 1.14 | 0.9 –1.5 | |
| Yes | 159 (34.9) | 90 (30.3) | 1.02 | 0.7 –1.4 | |
| Characteristic . | Vasectomy status . | . | ORa . | 95% CI . | |
|---|---|---|---|---|---|
| . | No (n = 456) . | Yes (n = 297) . | . | . | |
| Stage at diagnosis | |||||
| A | 66 (14.5)b | 48 (16.2) | 1.19 | 0.8 –1.8 | |
| B | 262 (57.5) | 177 (59.6) | 1.16 | 0.9 –1.5 | |
| C | 77 (16.9) | 47 (15.8) | 1.04 | 0.7 –1.6 | |
| D | 39 (8.6) | 18 (6.1) | 0.78 | 0.4 –1.4 | |
| Unk | 12 (2.6) | 7 (2.4) | |||
| Gleason grade | |||||
| 2–4 | 51 (11.2) | 35 (11.8) | 1.23 | 0.8 –2.0 | |
| 5–7 | 318 (69.7) | 228 (76.8) | 1.22 | 0.9 –1.6 | |
| 8–10 | 80 (17.5) | 31 (10.4) | 0.66 | 0.4 –1.0 | |
| Unk | 7 (1.5) | 3 (1.0) | |||
| Symptomsc at diagnosis | |||||
| No | 297 (65.1) | 206 (69.4) | 1.14 | 0.9 –1.5 | |
| Yes | 159 (34.9) | 90 (30.3) | 1.02 | 0.7 –1.4 | |
ORs for each stratum of cases compared to the same set of controls (438 with vasectomy, 265 without vasectomy), computed by polychotomous logistic regression; ORs adjusted for age (continuous), race, family history of prostate cancer (none, first-degree relative, second-degree relative only), and number of PSA blood tests within 5 years before reference date (0, 1–2, 3–4, ≥5).
Data represent the number of cases followed by the percentage of cases in parentheses.
One case had missing information on symptoms at diagnosis; this variable was based on whether the patient reported having any symptoms at the time of the initial physician visit which led to the diagnosis of prostate cancer.