Association-based analysis for D95N, E185Q, and R215W
| Sample and variant . | No. of carriers/total (frequency) . | Odds ratio (95% confidence interval) . | P . | |||
|---|---|---|---|---|---|---|
| D95N (Tampere) | ||||||
| Controls | 0 of 440 (0%) | — | — | |||
| Unselected prostate cancer | 1 of 613 (0.16%) | — | — | |||
| Familial prostate cancer | 1 of 121 (0.83%) | — | — | |||
| E185Q (Tampere) | ||||||
| Controls (G/C) | 79 of 200 (39.5%) | 1 | ||||
| Controls (C/C) | 32 of 200 (16.0%) | 1 | ||||
| Unselected prostate cancer (G/C) | 94 of 200 (47.0%) | 1.59 (0.86-2.91) | 0.14 | |||
| Unselected prostate cancer (C/C) | 24 of 200 (12.0%) | 1.23 (0.67-2.26) | 0.51 | |||
| Familial prostate cancer (G/C) | 63 of 121 (52.07%) | 1.42 (0.73-2.76) | 0.30 | |||
| Familial prostate cancer (C/C) | 18 of 121 (14.9%) | 0.80 (0.40-1.59) | 0.52 | |||
| R215W (Ulm) | ||||||
| Controls | 3 of 208 (1.44%) | 1 | ||||
| Unaffected familial | 1 of 111 (0.90%) | |||||
| Sporadic prostate cancer | 6 of 338 (1.78%) | 1.24 (0.31-4.99) | 0.77 | |||
| Familial prostate cancer | 2 of 139 (1.44%) | 1.0 (0.17-6.05) | 1.0 | |||
| Sample and variant . | No. of carriers/total (frequency) . | Odds ratio (95% confidence interval) . | P . | |||
|---|---|---|---|---|---|---|
| D95N (Tampere) | ||||||
| Controls | 0 of 440 (0%) | — | — | |||
| Unselected prostate cancer | 1 of 613 (0.16%) | — | — | |||
| Familial prostate cancer | 1 of 121 (0.83%) | — | — | |||
| E185Q (Tampere) | ||||||
| Controls (G/C) | 79 of 200 (39.5%) | 1 | ||||
| Controls (C/C) | 32 of 200 (16.0%) | 1 | ||||
| Unselected prostate cancer (G/C) | 94 of 200 (47.0%) | 1.59 (0.86-2.91) | 0.14 | |||
| Unselected prostate cancer (C/C) | 24 of 200 (12.0%) | 1.23 (0.67-2.26) | 0.51 | |||
| Familial prostate cancer (G/C) | 63 of 121 (52.07%) | 1.42 (0.73-2.76) | 0.30 | |||
| Familial prostate cancer (C/C) | 18 of 121 (14.9%) | 0.80 (0.40-1.59) | 0.52 | |||
| R215W (Ulm) | ||||||
| Controls | 3 of 208 (1.44%) | 1 | ||||
| Unaffected familial | 1 of 111 (0.90%) | |||||
| Sporadic prostate cancer | 6 of 338 (1.78%) | 1.24 (0.31-4.99) | 0.77 | |||
| Familial prostate cancer | 2 of 139 (1.44%) | 1.0 (0.17-6.05) | 1.0 | |||