Parental medication exposure and ras mutation among childhood ALL cases
| Parental Medication Exposure . | K-ras Mutation . | . | . | N-ras Mutation . | . | |||
|---|---|---|---|---|---|---|---|---|
| . | −Cases . | +Cases . | Adjusted OR (95% CI) . | +Cases . | Adjusted OR (95% CI) . | |||
| Mothers (n) | 710 | 40 | 89 | |||||
| Amphetamines or diet pills* | 38 | 1 | 0.6 (0.1-4.2) | 7 | 1.5 (0.6 -3.5) | |||
| Vitamins† | 618 | 36 | 1.2 (0.4-3.5) | 78 | 1.0 (0.5-2.0) | |||
| Iron supplements† | 220 | 18 | 1.9 (1.0-3.7) | 27 | 1.0 (0.6-1.6) | |||
| Antihistamines or allergy remedies* | 83 | 2 | 0.4 (0.1-1.6) | 11 | 1.0 (0.5-2.0) | |||
| Mind-altering drugs* | 45 | 5 | 2.4 (0.9-6.7) | 15 | 3.2 (1.7-6.1) | |||
| Fathers | 567 | 32 | 77 | |||||
| Amphetamines or diet pills | 8 | 1 | 2.4 (0.3-22.7) | 4 | 4.1 (1.1-15.0) | |||
| Vitamins | 147 | 11 | 1.5 (0.7-3.3) | 23 | 1.2 (0.7-2.0) | |||
| Antihistamines | 75 | 4 | 0.9 (0.3-2.9) | 9 | 0.8 (0.4-1.7) | |||
| Mind-altering drugs | 68 | 5 | 1.6 (0.6-4.7) | 18 | 2.0 (1.1-3.7) | |||
| Parental Medication Exposure . | K-ras Mutation . | . | . | N-ras Mutation . | . | |||
|---|---|---|---|---|---|---|---|---|
| . | −Cases . | +Cases . | Adjusted OR (95% CI) . | +Cases . | Adjusted OR (95% CI) . | |||
| Mothers (n) | 710 | 40 | 89 | |||||
| Amphetamines or diet pills* | 38 | 1 | 0.6 (0.1-4.2) | 7 | 1.5 (0.6 -3.5) | |||
| Vitamins† | 618 | 36 | 1.2 (0.4-3.5) | 78 | 1.0 (0.5-2.0) | |||
| Iron supplements† | 220 | 18 | 1.9 (1.0-3.7) | 27 | 1.0 (0.6-1.6) | |||
| Antihistamines or allergy remedies* | 83 | 2 | 0.4 (0.1-1.6) | 11 | 1.0 (0.5-2.0) | |||
| Mind-altering drugs* | 45 | 5 | 2.4 (0.9-6.7) | 15 | 3.2 (1.7-6.1) | |||
| Fathers | 567 | 32 | 77 | |||||
| Amphetamines or diet pills | 8 | 1 | 2.4 (0.3-22.7) | 4 | 4.1 (1.1-15.0) | |||
| Vitamins | 147 | 11 | 1.5 (0.7-3.3) | 23 | 1.2 (0.7-2.0) | |||
| Antihistamines | 75 | 4 | 0.9 (0.3-2.9) | 9 | 0.8 (0.4-1.7) | |||
| Mind-altering drugs | 68 | 5 | 1.6 (0.6-4.7) | 18 | 2.0 (1.1-3.7) | |||
Including those used only during 1 year before the index pregnancy, those used both before and during the index pregnancy, and those used only during the index pregnancy.
Including those used only during the index pregnancy, excluding those used during 1 year before the index pregnancy, and those used both before and during the index pregnancy.