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Table 4.

Parental medication exposure and ras mutation among childhood ALL cases

Parental Medication ExposureK-ras Mutation
N-ras Mutation
−Cases+CasesAdjusted OR (95% CI)+CasesAdjusted OR (95% CI)
Mothers (n710 40  89  
    Amphetamines or diet pills* 38 0.6 (0.1-4.2) 1.5 (0.6 -3.5) 
    Vitamins 618 36 1.2 (0.4-3.5) 78 1.0 (0.5-2.0) 
    Iron supplements 220 18 1.9 (1.0-3.7) 27 1.0 (0.6-1.6) 
    Antihistamines or allergy remedies* 83 0.4 (0.1-1.6) 11 1.0 (0.5-2.0) 
    Mind-altering drugs* 45 2.4 (0.9-6.7) 15 3.2 (1.7-6.1) 
Fathers 567 32  77  
    Amphetamines or diet pills 2.4 (0.3-22.7) 4.1 (1.1-15.0) 
    Vitamins 147 11 1.5 (0.7-3.3) 23 1.2 (0.7-2.0) 
    Antihistamines 75 0.9 (0.3-2.9) 0.8 (0.4-1.7) 
    Mind-altering drugs 68 1.6 (0.6-4.7) 18 2.0 (1.1-3.7) 
Parental Medication ExposureK-ras Mutation
N-ras Mutation
−Cases+CasesAdjusted OR (95% CI)+CasesAdjusted OR (95% CI)
Mothers (n710 40  89  
    Amphetamines or diet pills* 38 0.6 (0.1-4.2) 1.5 (0.6 -3.5) 
    Vitamins 618 36 1.2 (0.4-3.5) 78 1.0 (0.5-2.0) 
    Iron supplements 220 18 1.9 (1.0-3.7) 27 1.0 (0.6-1.6) 
    Antihistamines or allergy remedies* 83 0.4 (0.1-1.6) 11 1.0 (0.5-2.0) 
    Mind-altering drugs* 45 2.4 (0.9-6.7) 15 3.2 (1.7-6.1) 
Fathers 567 32  77  
    Amphetamines or diet pills 2.4 (0.3-22.7) 4.1 (1.1-15.0) 
    Vitamins 147 11 1.5 (0.7-3.3) 23 1.2 (0.7-2.0) 
    Antihistamines 75 0.9 (0.3-2.9) 0.8 (0.4-1.7) 
    Mind-altering drugs 68 1.6 (0.6-4.7) 18 2.0 (1.1-3.7) 
*

Including those used only during 1 year before the index pregnancy, those used both before and during the index pregnancy, and those used only during the index pregnancy.

Including those used only during the index pregnancy, excluding those used during 1 year before the index pregnancy, and those used both before and during the index pregnancy.

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