Any and hours per week of recreational physical activity and incident cancer of the proximal colon, distal colon, and rectum, number of cases and multivariate-adjusted RR and 95% CI, CPS II Nutrition Cohort men and women, 1992-1993 to 1999
| . | Men and women . | . | . | . | . | . | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| . | Proximal colon . | . | Distal colon . | . | Rectosigmoid and rectum . | . | ||||||
| Recreational physical activity in the year before study enrollment . | No. cases . | Multivariate-adjusted* RR (95% CI) . | No. cases . | Multivariate-adjusted* RR (95% CI) . | No. cases . | Multivariate-adjusted* RR (95% CI) . | ||||||
| Total | 505 | 339 | 390 | |||||||||
| Recreational physical activity | ||||||||||||
| No activity | 67 | 1.00 (reference) | 41 | 1.00 (reference) | 63 | 1.00 (reference) | ||||||
| Any activity† | 438 | 0.77 (0.59-1.01) | 298 | 0.91 (0.65-1.28) | 327 | 0.70 (0.53-0.93) | ||||||
| Recreational physical activity† (h/wk) | ||||||||||||
| No activity | 67 | 1.00 (reference) | 41 | 1.00 (reference) | 63 | 1.00 (reference) | ||||||
| <2 | 156 | 0.83 (0.62-1.10) | 110 | 1.00 (0.69-1.43) | 112 | 0.72 (0.52-0.98) | ||||||
| 2-3 | 80 | 0.73 (0.52-1.01) | 54 | 0.87 (0.57-1.32) | 60 | 0.68 (0.47-0.97) | ||||||
| 4-6 | 123 | 0.85 (0.62-1.15) | 74 | 0.89 (0.60-1.32) | 68 | 0.59 (0.41-0.83) | ||||||
| ≥7 | 79 | 0.63 (0.45-0.88) | 60 | 0.82 (0.55-1.24) | 87 | 0.83 (0.59-1.16) | ||||||
| P for trend, with and without reference group | 0.008, 0.03 | 0.15, 0.20 | 0.73, 0.45 | |||||||||
| Type of recreational activities (h/wk) | ||||||||||||
| No activity | 67 | 1.00 (reference) | 41 | 1.00 (reference) | 63 | 1.00 (reference) | ||||||
| Walking only | ||||||||||||
| <4 | 145 | 0.84 (0.62-1.12) | 95 | 0.93 (0.64-1.35) | 100 | 0.71 (0.51-0.97) | ||||||
| 4-6 | 70 | 0.82 (0.58-1.15) | 48 | 0.97 (0.63-1.48) | 41 | 0.60 (0.40-0.90) | ||||||
| ≥7 | 38 | 0.83 (0.56-1.25) | 30 | 1.08 (0.67-1.73) | 36 | 0.89 (0.59-1.34) | ||||||
| P for trend, with and without reference group | 0.44, 0.90 | 0.84, 0.56 | 0.44, 0.70 | |||||||||
| Walking plus other activities | ||||||||||||
| <4 | 74 | 0.69 (0.49-0.97) | 54 | 0.89 (0.59-1.35) | 57 | 0.67 (0.46-0.97) | ||||||
| 4-6 | 44 | 0.80 (0.54-1.18) | 22 | 0.71 (0.42-1.21) | 23 | 0.53 (0.33-0.87) | ||||||
| ≥7 | 39 | 0.50 (0.33-0.75) | 24 | 0.55 (0.33-0.92) | 46 | 0.72 (0.49-1.08) | ||||||
| P for trend, with and without reference group | 0.008, 0.12 | 0.15, 0.27 | 0.30, 0.32 | |||||||||
| . | Men and women . | . | . | . | . | . | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| . | Proximal colon . | . | Distal colon . | . | Rectosigmoid and rectum . | . | ||||||
| Recreational physical activity in the year before study enrollment . | No. cases . | Multivariate-adjusted* RR (95% CI) . | No. cases . | Multivariate-adjusted* RR (95% CI) . | No. cases . | Multivariate-adjusted* RR (95% CI) . | ||||||
| Total | 505 | 339 | 390 | |||||||||
| Recreational physical activity | ||||||||||||
| No activity | 67 | 1.00 (reference) | 41 | 1.00 (reference) | 63 | 1.00 (reference) | ||||||
| Any activity† | 438 | 0.77 (0.59-1.01) | 298 | 0.91 (0.65-1.28) | 327 | 0.70 (0.53-0.93) | ||||||
| Recreational physical activity† (h/wk) | ||||||||||||
| No activity | 67 | 1.00 (reference) | 41 | 1.00 (reference) | 63 | 1.00 (reference) | ||||||
| <2 | 156 | 0.83 (0.62-1.10) | 110 | 1.00 (0.69-1.43) | 112 | 0.72 (0.52-0.98) | ||||||
| 2-3 | 80 | 0.73 (0.52-1.01) | 54 | 0.87 (0.57-1.32) | 60 | 0.68 (0.47-0.97) | ||||||
| 4-6 | 123 | 0.85 (0.62-1.15) | 74 | 0.89 (0.60-1.32) | 68 | 0.59 (0.41-0.83) | ||||||
| ≥7 | 79 | 0.63 (0.45-0.88) | 60 | 0.82 (0.55-1.24) | 87 | 0.83 (0.59-1.16) | ||||||
| P for trend, with and without reference group | 0.008, 0.03 | 0.15, 0.20 | 0.73, 0.45 | |||||||||
| Type of recreational activities (h/wk) | ||||||||||||
| No activity | 67 | 1.00 (reference) | 41 | 1.00 (reference) | 63 | 1.00 (reference) | ||||||
| Walking only | ||||||||||||
| <4 | 145 | 0.84 (0.62-1.12) | 95 | 0.93 (0.64-1.35) | 100 | 0.71 (0.51-0.97) | ||||||
| 4-6 | 70 | 0.82 (0.58-1.15) | 48 | 0.97 (0.63-1.48) | 41 | 0.60 (0.40-0.90) | ||||||
| ≥7 | 38 | 0.83 (0.56-1.25) | 30 | 1.08 (0.67-1.73) | 36 | 0.89 (0.59-1.34) | ||||||
| P for trend, with and without reference group | 0.44, 0.90 | 0.84, 0.56 | 0.44, 0.70 | |||||||||
| Walking plus other activities | ||||||||||||
| <4 | 74 | 0.69 (0.49-0.97) | 54 | 0.89 (0.59-1.35) | 57 | 0.67 (0.46-0.97) | ||||||
| 4-6 | 44 | 0.80 (0.54-1.18) | 22 | 0.71 (0.42-1.21) | 23 | 0.53 (0.33-0.87) | ||||||
| ≥7 | 39 | 0.50 (0.33-0.75) | 24 | 0.55 (0.33-0.92) | 46 | 0.72 (0.49-1.08) | ||||||
| P for trend, with and without reference group | 0.008, 0.12 | 0.15, 0.27 | 0.30, 0.32 | |||||||||
Models included age, sex, education, exercise level in 1982, cigarette smoking, alcohol, red meat, folate, fiber, multivitamin use in 1982, and hormone replacement therapy (women).
Included walking, jogging/running, lap swimming, tennis or racquetball, bicycling/stationary bike, aerobics/calisthenics, and dancing.