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Table 4.

Changes on the expression of osteogenic associated genes

Accession no.Unigene IDSymbolDescriptionFold of change
Up-regulated (nine genes)     
    R55809 Hs.284122 WIF1 WNT inhibitory factor 1 31.12 
    AA858175 Hs.535845 RUNX2 Runt-related transcription factor 2 25.80 
    H96738 Hs.116471 CDH11 Cadherin 11, type 2, OB-cadherin (osteoblast) 9.82 
    AA775616  SPP1 Secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) 7.45 
    N20203 Hs.471119 BMPR2 Bone morphogenetic protein receptor, type II (serine/threonine kinase) 5.35 
    TGF-β  TGFB Transforming growth factor-β 5.05 
    AA449300 Hs.481022 SFRP2 Secreted frizzled-related protein 2 4.71 
    AA463225 Hs.68879 BMP4 Bone morphogenetic protein 4 3.87 
    AA779480 Hs.494158 BMP8A Bone morphogenetic protein 8a 3.37 
Down-regulated (six genes)     
    AA194983 Hs.81791 TNFRSF11B Tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) −95.28 
    R38933 Hs.491582 PLAT Plasminogen activator, tissue −8.32 
    AA490172 Hs.489142 COL1A2 Collagen, type I, α2 −6.47 
    AA598601 Hs.450230 IGFBP3 Insulin-like growth factor binding protein 3 −5.96 
    AA143331 Hs.83169 MMP1 Matrix metalloproteinase 1 (interstitial collagenase) −5.66 
    AA936799 Hs.513617 MMP2 Matrix metalloproteinase 2 (gelatinase A, 72 kDa gelatinase, 72 kDa type IV collagenase) −5.46 
Accession no.Unigene IDSymbolDescriptionFold of change
Up-regulated (nine genes)     
    R55809 Hs.284122 WIF1 WNT inhibitory factor 1 31.12 
    AA858175 Hs.535845 RUNX2 Runt-related transcription factor 2 25.80 
    H96738 Hs.116471 CDH11 Cadherin 11, type 2, OB-cadherin (osteoblast) 9.82 
    AA775616  SPP1 Secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) 7.45 
    N20203 Hs.471119 BMPR2 Bone morphogenetic protein receptor, type II (serine/threonine kinase) 5.35 
    TGF-β  TGFB Transforming growth factor-β 5.05 
    AA449300 Hs.481022 SFRP2 Secreted frizzled-related protein 2 4.71 
    AA463225 Hs.68879 BMP4 Bone morphogenetic protein 4 3.87 
    AA779480 Hs.494158 BMP8A Bone morphogenetic protein 8a 3.37 
Down-regulated (six genes)     
    AA194983 Hs.81791 TNFRSF11B Tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) −95.28 
    R38933 Hs.491582 PLAT Plasminogen activator, tissue −8.32 
    AA490172 Hs.489142 COL1A2 Collagen, type I, α2 −6.47 
    AA598601 Hs.450230 IGFBP3 Insulin-like growth factor binding protein 3 −5.96 
    AA143331 Hs.83169 MMP1 Matrix metalloproteinase 1 (interstitial collagenase) −5.66 
    AA936799 Hs.513617 MMP2 Matrix metalloproteinase 2 (gelatinase A, 72 kDa gelatinase, 72 kDa type IV collagenase) −5.46 
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