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Table 1.

Top 50 up-regulated genes

Accession no.Unigene IDSymbolDescriptionFold of change
R55809 Hs.284122 WIF1 WNT inhibitory factor 1 31.12 
R53942 Hs.246506 SLC25A4 Solute carrier family 25, member 4 28.43 
AA858175 Hs.535845 RUNX2 Runt-related transcription factor 2 25.80 
AA156964 Hs.471200 NRP2 Neuropilin 2 19.22 
AA425628 Hs.77578 USP9X Ubiquitin specific protease 9, X-linked (fat facets-like, Drosophila) 17.23 
H06516 Hs.212838 A2M α-2-macroglobulin 16.64 
T51538 Hs.368592 SORL1 Sortilin-related receptor, L(DLR class) A repeats-containing 14.85 
AA677306 Hs.158560 TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250 kDa 13.32 
AI016456 Hs.333497 CYP2D7P1 Cytochrome P450, family 2, subfamily D, polypeptide 7 pseudogene 1 13.28 
AA442092 Hs.476018 CTNNB1 Catenin (cadherin-associated protein), β 1, 88 kDa 13.15 
AA055979 Hs.524484 ITGA7 Integrin, α 7 13.06 
AA490459 Hs.417948 TCN2 Transcobalamin II; macrocytic anemia 12.68 
AA464532 Hs.164226 THBS1 Thrombospondin 1 12.53 
AA705237 Hs.370480 ABCB7 ATP-binding cassette, subfamily B (MDR/TAP), member 7 12.20 
AA676805 Hs.336994 MTSS1 Metastasis suppressor 1 11.36 
AA404486 Hs.522767 SLC25A5 Solute carrier family 25, member 5 10.28 
AA487231 Hs.148641 CTSH Cathepsin H 10.14 
H96738 Hs.116471 CDH11 Cadherin 11, type 2, OB-cadherin (osteoblast) 9.82 
AA446600 Hs.136905 UREB1 HECT, UBA and WWE domain containing 1 9.70 
AA227885 Hs.80395 MAL Mal, T cell differentiation protein 8.97 
N29914 Hs.82002 EDNRB Endothelin receptor type B 8.93 
AA810225 Hs.552573 GPR30 G protein–coupled receptor 30 8.39 
AA452149 Hs.173135 DYRK2 Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 8.34 
AA443093 Hs.533683 FGFR2 Fibroblast growth factor receptor 2 (bacteria-expressed kinase, keratinocyte growth factor receptor, craniofacial dysostosis 1, Crouzon syndrome, Pfeiffer syndrome, Jackson-Weiss syndrome) 8.29 
AA682819 Hs.470171 ACVR2 Activin A receptor, type II 8.26 
AA970865 Hs.21145 ODAG GATA zinc finger domain containing 1 7.48 
AA775616  SPP1 Secreted phosphoprotein 1 (osteopontin, bone sialoprotein 1) 7.45 
N69689 Hs.310645 RAB1A RAB1A, member RAS oncogene family 7.40 
R85213 Hs.22543 UBE3A Ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome) 7.28 
AA706987 Hs.514806 GALNT1 UDP-N-acetyl-α-d-galactosamine: polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) 7.28 
R41839 Hs.154073 SLC35B1 Solute carrier family 35, member B1 7.27 
N71628 Hs.437905 SPIB Spi-B transcription factor (Spi-1/PU.1 related) 7.26 
AI129421 Hs.83077 IL18 Interleukin 18 (IFN-γ-inducing factor) 7.25 
AA101617 Hs.220971 FOSL2 FOS-like antigen 2 7.18 
AA180742 Hs.75318 TUBA1 Tubulin, α 1 (testis specific) 7.15 
AA446108 Hs.76753 ENG Endoglin (Osler-Rendu-Weber syndrome 1) 7.11 
T60048 Hs.516105 ACTG2 Actin, γ 2, smooth muscle, enteric 7.06 
AA454585 Hs.73965 SFRS2 Splicing factor, arginine/serine-rich 2 6.96 
AA418813 Hs.309090 SFRS7 Splicing factor, arginine/serine-rich 7, 35 kDa 6.93 
AA626845 Hs.380774 DDX3X DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked 6.82 
T66839 Hs.325846 FLJ11806 Nuclear protein UKp68 6.78 
T50498 Hs.433795 SHC1 SHC (Src homology 2 domain containing) transforming protein 1 6.73 
AA496691 Hs.76111 DAG1 Dystroglycan 1 (dystrophin-associated glycoprotein 1) 6.72 
AA598670 Hs.533273 UBE1 Ubiquitin-activating enzyme E1 (A1S9T and BN75 temperature sensitivity complementing) 6.63 
AA281784 Hs.518451 PIK3CD Phosphoinositide-3-kinase, catalytic, δ polypeptide 6.37 
H20138 Hs.503222 RAB6A RAB6A, member RAS oncogene family 6.35 
AA912448 Hs.46523 ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) 6.33 
N68166 Hs.185172 GNB2 Guanine nucleotide binding protein (G protein), β polypeptide 2 6.22 
AI392759 Hs.515840 DNMT3A DNA (cytosine-5-)-methyltransferase-3α 6.21 
AA281635 Hs.411311 IL24 Interleukin 24 6.16 
Accession no.Unigene IDSymbolDescriptionFold of change
R55809 Hs.284122 WIF1 WNT inhibitory factor 1 31.12 
R53942 Hs.246506 SLC25A4 Solute carrier family 25, member 4 28.43 
AA858175 Hs.535845 RUNX2 Runt-related transcription factor 2 25.80 
AA156964 Hs.471200 NRP2 Neuropilin 2 19.22 
AA425628 Hs.77578 USP9X Ubiquitin specific protease 9, X-linked (fat facets-like, Drosophila) 17.23 
H06516 Hs.212838 A2M α-2-macroglobulin 16.64 
T51538 Hs.368592 SORL1 Sortilin-related receptor, L(DLR class) A repeats-containing 14.85 
AA677306 Hs.158560 TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250 kDa 13.32 
AI016456 Hs.333497 CYP2D7P1 Cytochrome P450, family 2, subfamily D, polypeptide 7 pseudogene 1 13.28 
AA442092 Hs.476018 CTNNB1 Catenin (cadherin-associated protein), β 1, 88 kDa 13.15 
AA055979 Hs.524484 ITGA7 Integrin, α 7 13.06 
AA490459 Hs.417948 TCN2 Transcobalamin II; macrocytic anemia 12.68 
AA464532 Hs.164226 THBS1 Thrombospondin 1 12.53 
AA705237 Hs.370480 ABCB7 ATP-binding cassette, subfamily B (MDR/TAP), member 7 12.20 
AA676805 Hs.336994 MTSS1 Metastasis suppressor 1 11.36 
AA404486 Hs.522767 SLC25A5 Solute carrier family 25, member 5 10.28 
AA487231 Hs.148641 CTSH Cathepsin H 10.14 
H96738 Hs.116471 CDH11 Cadherin 11, type 2, OB-cadherin (osteoblast) 9.82 
AA446600 Hs.136905 UREB1 HECT, UBA and WWE domain containing 1 9.70 
AA227885 Hs.80395 MAL Mal, T cell differentiation protein 8.97 
N29914 Hs.82002 EDNRB Endothelin receptor type B 8.93 
AA810225 Hs.552573 GPR30 G protein–coupled receptor 30 8.39 
AA452149 Hs.173135 DYRK2 Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 8.34 
AA443093 Hs.533683 FGFR2 Fibroblast growth factor receptor 2 (bacteria-expressed kinase, keratinocyte growth factor receptor, craniofacial dysostosis 1, Crouzon syndrome, Pfeiffer syndrome, Jackson-Weiss syndrome) 8.29 
AA682819 Hs.470171 ACVR2 Activin A receptor, type II 8.26 
AA970865 Hs.21145 ODAG GATA zinc finger domain containing 1 7.48 
AA775616  SPP1 Secreted phosphoprotein 1 (osteopontin, bone sialoprotein 1) 7.45 
N69689 Hs.310645 RAB1A RAB1A, member RAS oncogene family 7.40 
R85213 Hs.22543 UBE3A Ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome) 7.28 
AA706987 Hs.514806 GALNT1 UDP-N-acetyl-α-d-galactosamine: polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) 7.28 
R41839 Hs.154073 SLC35B1 Solute carrier family 35, member B1 7.27 
N71628 Hs.437905 SPIB Spi-B transcription factor (Spi-1/PU.1 related) 7.26 
AI129421 Hs.83077 IL18 Interleukin 18 (IFN-γ-inducing factor) 7.25 
AA101617 Hs.220971 FOSL2 FOS-like antigen 2 7.18 
AA180742 Hs.75318 TUBA1 Tubulin, α 1 (testis specific) 7.15 
AA446108 Hs.76753 ENG Endoglin (Osler-Rendu-Weber syndrome 1) 7.11 
T60048 Hs.516105 ACTG2 Actin, γ 2, smooth muscle, enteric 7.06 
AA454585 Hs.73965 SFRS2 Splicing factor, arginine/serine-rich 2 6.96 
AA418813 Hs.309090 SFRS7 Splicing factor, arginine/serine-rich 7, 35 kDa 6.93 
AA626845 Hs.380774 DDX3X DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked 6.82 
T66839 Hs.325846 FLJ11806 Nuclear protein UKp68 6.78 
T50498 Hs.433795 SHC1 SHC (Src homology 2 domain containing) transforming protein 1 6.73 
AA496691 Hs.76111 DAG1 Dystroglycan 1 (dystrophin-associated glycoprotein 1) 6.72 
AA598670 Hs.533273 UBE1 Ubiquitin-activating enzyme E1 (A1S9T and BN75 temperature sensitivity complementing) 6.63 
AA281784 Hs.518451 PIK3CD Phosphoinositide-3-kinase, catalytic, δ polypeptide 6.37 
H20138 Hs.503222 RAB6A RAB6A, member RAS oncogene family 6.35 
AA912448 Hs.46523 ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) 6.33 
N68166 Hs.185172 GNB2 Guanine nucleotide binding protein (G protein), β polypeptide 2 6.22 
AI392759 Hs.515840 DNMT3A DNA (cytosine-5-)-methyltransferase-3α 6.21 
AA281635 Hs.411311 IL24 Interleukin 24 6.16 
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