BRCA2 expression and relationship with clinicopathologic variables in CRC
| . | BRCA2 expression (%) . | . | . | . | ||||
|---|---|---|---|---|---|---|---|---|
| . | n . | Negative (<5%) . | Positive (>5%) . | P . | ||||
| pT category | ||||||||
| pT1 | 20 | 1 (5) | 19 (95) | 0.62 | ||||
| pT2 | 53 | 7 (13) | 46 (87) | |||||
| pT3 | 189 | 18 (10) | 171 (90) | |||||
| pT4 | 20 | 1 (5) | 19 (95) | |||||
| pN category | ||||||||
| pN0 | 188 | 15 (8) | 173 (92) | 0.25 | ||||
| pN1 | 59 | 9 (15) | 50 (85) | |||||
| pN2 | 35 | 3 (9) | 32 (91) | |||||
| Stage | ||||||||
| Stage I | 62 | 6 (10) | 56 (90) | 0.29 | ||||
| Stage II | 124 | 8 (6) | 116 (94) | |||||
| Stage III/IV* | 96 | 13 (14) | 83 (86) | |||||
| Grading | ||||||||
| G1†/G2 | 210 | 15 (7) | 195 (93) | 0.018 | ||||
| G3/G4‡ | 72 | 12 (17) | 60 (83) | |||||
| Blood vessel invasion | ||||||||
| Negative | 259 | 24 (9) | 235 (91) | 0.15 | ||||
| Intramural | 10 | 0 (0) | 10 (100) | |||||
| Extramural | 13 | 3 (23) | 10 (77) | |||||
| Lymphatic vessel invasion | ||||||||
| Negative | 201 | 17 (8) | 184 (92) | 0.32 | ||||
| Positive | 81 | 10 (12) | 71 (88) | |||||
| Proliferative activity (Ki67) | ||||||||
| Low | 141 | 13 (9) | 128 (91) | 0.84 | ||||
| High | 141 | 14 (10) | 127 (90) | |||||
| . | BRCA2 expression (%) . | . | . | . | ||||
|---|---|---|---|---|---|---|---|---|
| . | n . | Negative (<5%) . | Positive (>5%) . | P . | ||||
| pT category | ||||||||
| pT1 | 20 | 1 (5) | 19 (95) | 0.62 | ||||
| pT2 | 53 | 7 (13) | 46 (87) | |||||
| pT3 | 189 | 18 (10) | 171 (90) | |||||
| pT4 | 20 | 1 (5) | 19 (95) | |||||
| pN category | ||||||||
| pN0 | 188 | 15 (8) | 173 (92) | 0.25 | ||||
| pN1 | 59 | 9 (15) | 50 (85) | |||||
| pN2 | 35 | 3 (9) | 32 (91) | |||||
| Stage | ||||||||
| Stage I | 62 | 6 (10) | 56 (90) | 0.29 | ||||
| Stage II | 124 | 8 (6) | 116 (94) | |||||
| Stage III/IV* | 96 | 13 (14) | 83 (86) | |||||
| Grading | ||||||||
| G1†/G2 | 210 | 15 (7) | 195 (93) | 0.018 | ||||
| G3/G4‡ | 72 | 12 (17) | 60 (83) | |||||
| Blood vessel invasion | ||||||||
| Negative | 259 | 24 (9) | 235 (91) | 0.15 | ||||
| Intramural | 10 | 0 (0) | 10 (100) | |||||
| Extramural | 13 | 3 (23) | 10 (77) | |||||
| Lymphatic vessel invasion | ||||||||
| Negative | 201 | 17 (8) | 184 (92) | 0.32 | ||||
| Positive | 81 | 10 (12) | 71 (88) | |||||
| Proliferative activity (Ki67) | ||||||||
| Low | 141 | 13 (9) | 128 (91) | 0.84 | ||||
| High | 141 | 14 (10) | 127 (90) | |||||