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Table 1.

Proportions of MO/MA subpopulations

MO/MA subpopulationPercentage of CD14+ MO/MA*
P value
ND PBEOC PBEOC ascEOC TAMND PB vs EOC PBEOC PB vs EOC ascND PB vs EOC ascND PB vs EOC TAMEOC PB vs EOC TAMEOC asc vs EOC TAM
CD14brightCD16HLA-DR+ 88%* 57% 33% 62% <0.01 NS <0.01 <0.01 NS NS 
CD14brightCD16HLA-DR 3% 36% 31% 6% <0.01 NS <0.01 NS 0.02 0.03 
CD14brightCD16+HLA-DR+ 4% 2% 19% 18% NS 0.04 0.02 <0.01 0.02 NS 
CD14brightCD16+HLA-DR <1% <1% 11% 1% NS <0.01 <0.01 <0.01 NS NS 
MO/MA subpopulationPercentage of CD14+ MO/MA*
P value
ND PBEOC PBEOC ascEOC TAMND PB vs EOC PBEOC PB vs EOC ascND PB vs EOC ascND PB vs EOC TAMEOC PB vs EOC TAMEOC asc vs EOC TAM
CD14brightCD16HLA-DR+ 88%* 57% 33% 62% <0.01 NS <0.01 <0.01 NS NS 
CD14brightCD16HLA-DR 3% 36% 31% 6% <0.01 NS <0.01 NS 0.02 0.03 
CD14brightCD16+HLA-DR+ 4% 2% 19% 18% NS 0.04 0.02 <0.01 0.02 NS 
CD14brightCD16+HLA-DR <1% <1% 11% 1% NS <0.01 <0.01 <0.01 NS NS 

Abbreviations: ND, normal donor; PB, peripheral blood; EOC, epithelial ovarian cancer patient; asc, ascites; TAM, tumor-associated macrophage; NS, not significant.

*

Percentages represent proportions of the total number of CD14+ MO/MA.

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