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Table 1.

Descriptive characteristics of prostate cancer cases (n = 75), subjects with BPH (n = 75), and controls subjects (n = 150)

VariableCasesBPHControlsP
Stage, n (%)     
    I 8 (11)    
    II 45 (63)    
    III 13 (18)    
    IV 5 (7)    
Gleason grade, n (%)     
    Low (2, 3, 4) 5 (7)    
    Intermediate (5, 6, 7) 48 (67)    
    High (8, 9, 10) 19 (26)    
PSA, ng/mL (median ± SE) 11.6 ± 4.9*† 5.9 ± 0.4 2.4 ± 0.3 <0.01 
Testosterone, ng/dL (age-standardized median ± SE) 314 ± 21 336 ± 21 298 ± 15 0.06 
Descriptive characteristics     
    Age, y (mean ± SD) 74.0 ± 8.2* 70.0 ± 6.5* 64.0 ± 8.3 <0.01 
    BMI, kg/m2 (mean ± SD) 26.2 ± 3.2* 27.0 ± 3.5 27.6 ± 3.5 0.04 
    Current smoker, n/N (%) 20/66 (30) 20/72 (28) 44/120 (37) 0.40 
    Alcohol use, n/N (%) 9/43 (21) 17/61 (28) 19/72 (26) 0.71 
Metabolic (mean ± SD)     
    Adiponectin, ng/mL 7.4 ± 5.0*† 11.5 ± 6.4 12.8 ± 8.0 0.04 
    Insulin, μIU/mL 19.0 ± 27.0 13.1 ± 10.9 19.5 ± 23.3 0.15 
    Glucose, mg/dL 109 ± 40 105 ± 36 111 ± 40 0.60 
Lipid profile (mean ± SD)     
    Total cholesterol, mg/dL 198 ± 43 197 ± 44 207 ± 45 0.35 
    HDL cholesterol, mg/dL 51 ± 14 52 ± 13 49 ± 14 0.31 
    LDL cholesterol, mg/dL 128 ± 39 124 ± 39 138 ± 42 0.11 
    Triglycerides, mg/dL 124 ± 78 132 ± 86 132 ± 55 0.30 
VariableCasesBPHControlsP
Stage, n (%)     
    I 8 (11)    
    II 45 (63)    
    III 13 (18)    
    IV 5 (7)    
Gleason grade, n (%)     
    Low (2, 3, 4) 5 (7)    
    Intermediate (5, 6, 7) 48 (67)    
    High (8, 9, 10) 19 (26)    
PSA, ng/mL (median ± SE) 11.6 ± 4.9*† 5.9 ± 0.4 2.4 ± 0.3 <0.01 
Testosterone, ng/dL (age-standardized median ± SE) 314 ± 21 336 ± 21 298 ± 15 0.06 
Descriptive characteristics     
    Age, y (mean ± SD) 74.0 ± 8.2* 70.0 ± 6.5* 64.0 ± 8.3 <0.01 
    BMI, kg/m2 (mean ± SD) 26.2 ± 3.2* 27.0 ± 3.5 27.6 ± 3.5 0.04 
    Current smoker, n/N (%) 20/66 (30) 20/72 (28) 44/120 (37) 0.40 
    Alcohol use, n/N (%) 9/43 (21) 17/61 (28) 19/72 (26) 0.71 
Metabolic (mean ± SD)     
    Adiponectin, ng/mL 7.4 ± 5.0*† 11.5 ± 6.4 12.8 ± 8.0 0.04 
    Insulin, μIU/mL 19.0 ± 27.0 13.1 ± 10.9 19.5 ± 23.3 0.15 
    Glucose, mg/dL 109 ± 40 105 ± 36 111 ± 40 0.60 
Lipid profile (mean ± SD)     
    Total cholesterol, mg/dL 198 ± 43 197 ± 44 207 ± 45 0.35 
    HDL cholesterol, mg/dL 51 ± 14 52 ± 13 49 ± 14 0.31 
    LDL cholesterol, mg/dL 128 ± 39 124 ± 39 138 ± 42 0.11 
    Triglycerides, mg/dL 124 ± 78 132 ± 86 132 ± 55 0.30 

Abbreviations: PSA, prostate-specific antigen; HDL, high-density lipoprotein; LDL, low-density lipoprotein.

*

P < 0.05 for Bonferroni corrected post hoc comparison with controls.

†

P < 0.05 for Bonferroni corrected post hoc comparison with BPH subjects.

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