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Table 4

Variables associated multivariately with breast cancer death and development of invasive cancer in either breast after a primary DCIS of the breast

VariableBreast cancer death OR (95% CI) [cases/controls]Ipsilateral cancer OR (95% CI) [cases/controls]Contralateral cancer OR (95% CI) [cases/controls]
Total [39/99] [70/185] [48/129] 
Age    
 <50 yr 1.6 (0.8–8.3) [13/37] 0.7 (0.2–2.4) [19/69] 0.7 (0.2–2.7) [17/51] 
 50–59 yr Refa [7/28] Ref [17/37] Ref [13/26] 
 >59 yr 1.2 (0.2–7.5) [19/34] 0.9 (0.2–3.4) [34/79] 1.2 (0.3–4.3) [18/52] 
Size, ≥25 mm vs. <25 mm 2.9 (0.8–10.1) [24/65] 2.3 (0.7–7.0) [43/117] 1.7 (0.5–5.1) [25/73] 
Treatment    
 BCS Ref [13/32] Ref [48/60] Ref [10/29] 
 BCS + XRT 1.4 (0.1–18.1) [1/9] 0.1 (0.0–1.0) [2/13] 3.6 (0.3–43.5) [6/4] 
 Mastectomy 1.8 (0.4–7.6) [25/57] 0.1 (0.0–0.5) [18/104] 0.7 (0.2–2.9) [30/82] 
VariableBreast cancer death OR (95% CI) [cases/controls]Ipsilateral cancer OR (95% CI) [cases/controls]Contralateral cancer OR (95% CI) [cases/controls]
Total [39/99] [70/185] [48/129] 
Age    
 <50 yr 1.6 (0.8–8.3) [13/37] 0.7 (0.2–2.4) [19/69] 0.7 (0.2–2.7) [17/51] 
 50–59 yr Refa [7/28] Ref [17/37] Ref [13/26] 
 >59 yr 1.2 (0.2–7.5) [19/34] 0.9 (0.2–3.4) [34/79] 1.2 (0.3–4.3) [18/52] 
Size, ≥25 mm vs. <25 mm 2.9 (0.8–10.1) [24/65] 2.3 (0.7–7.0) [43/117] 1.7 (0.5–5.1) [25/73] 
Treatment    
 BCS Ref [13/32] Ref [48/60] Ref [10/29] 
 BCS + XRT 1.4 (0.1–18.1) [1/9] 0.1 (0.0–1.0) [2/13] 3.6 (0.3–43.5) [6/4] 
 Mastectomy 1.8 (0.4–7.6) [25/57] 0.1 (0.0–0.5) [18/104] 0.7 (0.2–2.9) [30/82] 
a

Ref, Reference group with an odds ratio 1.0.

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