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Table 3

Summary ORs for various contrasts

ContrastComparisons (n)Random effects OR (95% CI)Fixed effects OR (95% CI)
A2 versus A1 alleles 12 (10,318) 1.08 (0.95–1.22)a 1.04 (0.96–1.13) 
 European 7 (8,052) 1.04 (0.92–1.18) 1.03 (0.94–1.13) 
 Asian 2 (1,772) 1.06 (0.66–1.71)a 0.99 (0.82–1.20) 
 African 3 (494) 1.56 (1.07–2.28) 1.56 (1.07–2.28) 
A2/A2 versus A1/A1 12 (2,673) 1.15 (0.91–1.46) 1.09 (0.92–1.29) 
A2/A2 versus (A1/A2+A1/A1) 12 (5,159) 1.08 (0.92–1.24) 1.07 (0.92–1.24) 
(A1/A2+A2/A2) versus A1/A1 12 (5,159) 1.11 (0.90–1.38)b 1.05 (0.93–1.18) 
ContrastComparisons (n)Random effects OR (95% CI)Fixed effects OR (95% CI)
A2 versus A1 alleles 12 (10,318) 1.08 (0.95–1.22)a 1.04 (0.96–1.13) 
 European 7 (8,052) 1.04 (0.92–1.18) 1.03 (0.94–1.13) 
 Asian 2 (1,772) 1.06 (0.66–1.71)a 0.99 (0.82–1.20) 
 African 3 (494) 1.56 (1.07–2.28) 1.56 (1.07–2.28) 
A2/A2 versus A1/A1 12 (2,673) 1.15 (0.91–1.46) 1.09 (0.92–1.29) 
A2/A2 versus (A1/A2+A1/A1) 12 (5,159) 1.08 (0.92–1.24) 1.07 (0.92–1.24) 
(A1/A2+A2/A2) versus A1/A1 12 (5,159) 1.11 (0.90–1.38)b 1.05 (0.93–1.18) 
a

Heterogeneity, 0.01 < P < 0.10.

b

Heterogeneity, P < 0.01.

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