Mean plasma levels of IGF-1, IGFBP-3, and IGF-1:IGFBP-3 molar ratio by intake of nutrients in quintiles in male health professionals
| Nutrienta . | Median daily intake . | IGF-1 (ng/mL) . | IGFBP-3 (ng/mL) . | IGF-1:IGFBP-3 (molar ratio) . |
|---|---|---|---|---|
| Total Fat (g) | ||||
| 47.8 | 188 | 3129 | 0.234 | |
| 58.4 | 184 | 3218 | 0.225 | |
| 66.7 | 181 | 3069 | 0.230 | |
| 74.0 | 186 | 3129 | 0.232 | |
| 84.0 | 179 | 3058 | 0.227 | |
| P (trend) | (0.16) | (0.24) | (0.54) | |
| Carbohydrate (g) | ||||
| 192.6 | 181 | 3209 | 0.220 | |
| 232.8 | 184 | 3087 | 0.233 | |
| 254.8 | 179 | 3113 | 0.226 | |
| 277.9 | 185 | 3058 | 0.236 | |
| 310.0 | 189 | 3168 | 0.232 | |
| P (trend) | (0.13) | (0.97) | (0.04) | |
| Protein (g) | ||||
| 69.1 | 173 | 3082 | 0.220 | |
| 79.5 | 177 | 3043 | 0.227 | |
| 85.9 | 182 | 3081 | 0.230 | |
| 93.8 | 187 | 3178 | 0.230 | |
| 107.1 | 201 | 3257 | 0.242 | |
| P (trend) | (<0.0001) | (0.01) | (<0.0001) | |
| Animal protein (g) | ||||
| 39.2 | 168 | 3042 | 0.217 | |
| 51.3 | 181 | 3113 | 0.226 | |
| 59.1 | 181 | 3032 | 0.233 | |
| 67.2 | 190 | 3190 | 0.231 | |
| 81.7 | 200 | 3273 | 0.241 | |
| P (trend) | (<0.0001) | (0.01) | (<0.0001) | |
| Vegetable protein (g) | ||||
| 20.2 | 173 | 3114 | 0.217 | |
| 23.9 | 183 | 3086 | 0.230 | |
| 27.0 | 179 | 3100 | 0.228 | |
| 30.0 | 191 | 3224 | 0.231 | |
| 36.0 | 194 | 3126 | 0.242 | |
| P (trend) | (<0.0002) | (0.59) | (<0.0001) |
| Nutrienta . | Median daily intake . | IGF-1 (ng/mL) . | IGFBP-3 (ng/mL) . | IGF-1:IGFBP-3 (molar ratio) . |
|---|---|---|---|---|
| Total Fat (g) | ||||
| 47.8 | 188 | 3129 | 0.234 | |
| 58.4 | 184 | 3218 | 0.225 | |
| 66.7 | 181 | 3069 | 0.230 | |
| 74.0 | 186 | 3129 | 0.232 | |
| 84.0 | 179 | 3058 | 0.227 | |
| P (trend) | (0.16) | (0.24) | (0.54) | |
| Carbohydrate (g) | ||||
| 192.6 | 181 | 3209 | 0.220 | |
| 232.8 | 184 | 3087 | 0.233 | |
| 254.8 | 179 | 3113 | 0.226 | |
| 277.9 | 185 | 3058 | 0.236 | |
| 310.0 | 189 | 3168 | 0.232 | |
| P (trend) | (0.13) | (0.97) | (0.04) | |
| Protein (g) | ||||
| 69.1 | 173 | 3082 | 0.220 | |
| 79.5 | 177 | 3043 | 0.227 | |
| 85.9 | 182 | 3081 | 0.230 | |
| 93.8 | 187 | 3178 | 0.230 | |
| 107.1 | 201 | 3257 | 0.242 | |
| P (trend) | (<0.0001) | (0.01) | (<0.0001) | |
| Animal protein (g) | ||||
| 39.2 | 168 | 3042 | 0.217 | |
| 51.3 | 181 | 3113 | 0.226 | |
| 59.1 | 181 | 3032 | 0.233 | |
| 67.2 | 190 | 3190 | 0.231 | |
| 81.7 | 200 | 3273 | 0.241 | |
| P (trend) | (<0.0001) | (0.01) | (<0.0001) | |
| Vegetable protein (g) | ||||
| 20.2 | 173 | 3114 | 0.217 | |
| 23.9 | 183 | 3086 | 0.230 | |
| 27.0 | 179 | 3100 | 0.228 | |
| 30.0 | 191 | 3224 | 0.231 | |
| 36.0 | 194 | 3126 | 0.242 | |
| P (trend) | (<0.0002) | (0.59) | (<0.0001) |
Protein, carbohydrate, and fat are adjusted for total energy. All results are adjusted for age and laboratory run. Animal and vegetable protein intakes are adjusted for each other.