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Table 2

ORs and 95% CIs for prostate cancer associated with cigarette smoking

Smoking variableCases, n (%)Controls, n (%)ORa (95% CI)
Smoking status    
 Nonsmoker 281 (37) 266 (38) Referent 
 Former smoker 349 (46) 322 (46) 1.0 (0.8–1.3) 
 Current smoker 123 (16) 115 (16) 1.4 (1.0–2.0) 
Smoking duration (yr)b    
 Nonsmokers 281 (38) 266 (38) Referent 
 <10 73 (10) 68 (10) 0.9 (0.6–1.4) 
 10–19 113 (15) 100 (14) 1.1 (0.8–1.5) 
 20–29 89 (12) 98 (14) 1.0 (0.7–1.4) 
 30–39 111 (14) 103 (14) 1.3 (0.9–1.8) 
 ≥40 86 (11) 68 (10) 1.5 (1.0–2.2) 
Cigarettes/dayc    
 Nonsmokers 281 (37) 266 (38) Referent 
 1–10 91 (12) 75 (11) 1.1 (0.8–1.6) 
 11–20 216 (29) 230 (33) 1.0 (0.8–1.3) 
 21–30 74 (10) 75 (11) 1.1 (0.7–1.7) 
 31–40 62 (8) 37 (5) 1.8 (1.1–2.9) 
 >40 29 (4) 20 (3) 1.5 (0.8–2.8) 
Pack-years of smokingd    
 Nonsmoker 281 (37) 266 (38) Referent 
 ≤10 122 (16) 93 (13) 1.1 (0.8–1.6) 
 11–20 65 (9) 92 (13) 0.7 (0.5–1.1) 
 21–30 72 (10) 76 (11) 1.0 (0.7–1.5) 
 31–40 73 (10) 73 (10) 1.1 (0.8–1.7) 
 >40 140 (19) 103 (15) 1.6 (1.1–2.2) 
Years since smoking cessatione    
 Nonsmoker 281 (37) 266 (38) Referent 
 Current smoker 123 (16) 115 (16) 1.4 (1.0–2.0) 
 <10 80 (11) 73 (10) 1.2 (0.8–1.7) 
 10–19 98 (13) 94 (13) 1.1 (0.8–1.6) 
 20–29 95 (13) 86 (12) 1.0 (0.7–1.5) 
 ≥30 76 (10) 69 (10) 0.8 (0.6–1.2) 
Smoking variableCases, n (%)Controls, n (%)ORa (95% CI)
Smoking status    
 Nonsmoker 281 (37) 266 (38) Referent 
 Former smoker 349 (46) 322 (46) 1.0 (0.8–1.3) 
 Current smoker 123 (16) 115 (16) 1.4 (1.0–2.0) 
Smoking duration (yr)b    
 Nonsmokers 281 (38) 266 (38) Referent 
 <10 73 (10) 68 (10) 0.9 (0.6–1.4) 
 10–19 113 (15) 100 (14) 1.1 (0.8–1.5) 
 20–29 89 (12) 98 (14) 1.0 (0.7–1.4) 
 30–39 111 (14) 103 (14) 1.3 (0.9–1.8) 
 ≥40 86 (11) 68 (10) 1.5 (1.0–2.2) 
Cigarettes/dayc    
 Nonsmokers 281 (37) 266 (38) Referent 
 1–10 91 (12) 75 (11) 1.1 (0.8–1.6) 
 11–20 216 (29) 230 (33) 1.0 (0.8–1.3) 
 21–30 74 (10) 75 (11) 1.1 (0.7–1.7) 
 31–40 62 (8) 37 (5) 1.8 (1.1–2.9) 
 >40 29 (4) 20 (3) 1.5 (0.8–2.8) 
Pack-years of smokingd    
 Nonsmoker 281 (37) 266 (38) Referent 
 ≤10 122 (16) 93 (13) 1.1 (0.8–1.6) 
 11–20 65 (9) 92 (13) 0.7 (0.5–1.1) 
 21–30 72 (10) 76 (11) 1.0 (0.7–1.5) 
 31–40 73 (10) 73 (10) 1.1 (0.8–1.7) 
 >40 140 (19) 103 (15) 1.6 (1.1–2.2) 
Years since smoking cessatione    
 Nonsmoker 281 (37) 266 (38) Referent 
 Current smoker 123 (16) 115 (16) 1.4 (1.0–2.0) 
 <10 80 (11) 73 (10) 1.2 (0.8–1.7) 
 10–19 98 (13) 94 (13) 1.1 (0.8–1.6) 
 20–29 95 (13) 86 (12) 1.0 (0.7–1.5) 
 ≥30 76 (10) 69 (10) 0.8 (0.6–1.2) 
a

ORs adjusted for age, race, family history of prostate cancer, history of PSA testing >1 year before reference date, and history of BPH.

b

Trend test for smoking duration P = 0.07.

c

Trend test for cigarettes per day P = 0.09.

d

Pack-years = years smoked × cigarettes/day / 20; trend test for pack-years of smoking P = 0.03.

e

Trend test for years since smoking cessation P = 0.02.

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