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Table 2

HER-2/neu gene amplification in cases and controlsa

HER-2/neu amplificationDCIS casesbDCIS controlsbORc95% CIP
No 72 (74) 59 (60) 1.0 — — 
Yes 25 (26) 39 (40) 0.35 0.17–0.72 0.004 
HER-2/neu amplificationDCIS casesbDCIS controlsbORc95% CIP
No 72 (74) 59 (60) 1.0 — — 
Yes 25 (26) 39 (40) 0.35 0.17–0.72 0.004 
a

OR, odds ratio; CI, confidence interval.

b

Cases, DCIS with invasive cancer; controls, DCIS alone.

c

Odds ratios were adjusted for pathologic nuclear grade and quantitative morphometric nuclear grade.

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