American Association for Cancer Research

Table 2

HER-2/neu gene amplification in cases and controls^a

HER-2/neu amplification	DCIS cases^b	DCIS controls^b	OR^c	95% CI	P
No	72 (74)	59 (60)	1.0	—	—
Yes	25 (26)	39 (40)	0.35	0.17–0.72	0.004

HER-2/neu amplification	DCIS cases^b	DCIS controls^b	OR^c	95% CI	P
No	72 (74)	59 (60)	1.0	—	—
Yes	25 (26)	39 (40)	0.35	0.17–0.72	0.004

OR, odds ratio; CI, confidence interval.

Cases, DCIS with invasive cancer; controls, DCIS alone.

Odds ratios were adjusted for pathologic nuclear grade and quantitative morphometric nuclear grade.