American Association for Cancer Research

Table 1

Mean cord serum hormone concentrations in pre-eclamptic and uncomplicated pregnancies

Hormone	Pre-eclampsia (N = 86)	Uncomplicated pregnancy (N = 86)	P
DHEA (ng/dL)
Median (range)	454 (124–1,598)	531 (103–1,470)
Adjusted mean^a (95% CI^b)	462 (332–642)	447 (328–609)	0.70
DHEAS (μg/dl)
Median (range)	151 (18–709)	187 (20–885)
Adjusted mean^a (95% CI)	132 (80–220)	139 (87–224)	0.68
Androstenedione (ng/dl)
Median (range)	341 (158–1,644)	344 (91–996)
Adjusted mean^a (95% CI)	338 (251–454)	323 (245–426)	0.54
Testosterone (ng/dl)
Median (range)	22.0 (6–187)	20.5 (2–166)
Adjusted mean^a (95% CI)	19.3 (11.4–32.9)	15.7 (9.6–25.9)	0.12
Estradiol (pg/ml)
Median (range)	11,805 (3,332–44,431)	9,510 (402–81,083)
Adjusted mean^a (95% CI)	9,901 (5,468–17,929)	7,526 (4,315–13,124)	0.06
Estrone (pg/ml)
Median (range)	26,356 (4,848–151,824)	30,815 (2,753–147,865)
Adjusted mean^a (95% CI)	27,574 (15,549–48,899)	28,135 (16,451–48,117)	0.89
Estriol (ng/ml)
Median (range)	188 (54–755)	223 (44.7–768)
Adjusted mean^a (95% CI)	276 (174–438)	303 (199–461)	0.43

Hormone	Pre-eclampsia (N = 86)	Uncomplicated pregnancy (N = 86)	P
DHEA (ng/dL)
Median (range)	454 (124–1,598)	531 (103–1,470)
Adjusted mean^a (95% CI^b)	462 (332–642)	447 (328–609)	0.70
DHEAS (μg/dl)
Median (range)	151 (18–709)	187 (20–885)
Adjusted mean^a (95% CI)	132 (80–220)	139 (87–224)	0.68
Androstenedione (ng/dl)
Median (range)	341 (158–1,644)	344 (91–996)
Adjusted mean^a (95% CI)	338 (251–454)	323 (245–426)	0.54
Testosterone (ng/dl)
Median (range)	22.0 (6–187)	20.5 (2–166)
Adjusted mean^a (95% CI)	19.3 (11.4–32.9)	15.7 (9.6–25.9)	0.12
Estradiol (pg/ml)
Median (range)	11,805 (3,332–44,431)	9,510 (402–81,083)
Adjusted mean^a (95% CI)	9,901 (5,468–17,929)	7,526 (4,315–13,124)	0.06
Estrone (pg/ml)
Median (range)	26,356 (4,848–151,824)	30,815 (2,753–147,865)
Adjusted mean^a (95% CI)	27,574 (15,549–48,899)	28,135 (16,451–48,117)	0.89
Estriol (ng/ml)
Median (range)	188 (54–755)	223 (44.7–768)
Adjusted mean^a (95% CI)	276 (174–438)	303 (199–461)	0.43

Adjusted means are geometric and from models that include a variable representing the individual match, race (white/other), parity (nulliparous, 1, 2+), gravidity (1, 2, 3, 4+), smoking (yes/no), weeks of gestation (continuous) and hours of labor (continuous).

CI, confidence interval.

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