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Table 1

Mean cord serum hormone concentrations in pre-eclamptic and uncomplicated pregnancies

HormonePre-eclampsia (N = 86)Uncomplicated pregnancy (N = 86)P
DHEA (ng/dL)    
 Median (range) 454 (124–1,598) 531 (103–1,470)  
 Adjusted meana (95% CIb462 (332–642) 447 (328–609) 0.70 
DHEAS (μg/dl)    
 Median (range) 151 (18–709) 187 (20–885)  
 Adjusted meana (95% CI) 132 (80–220) 139 (87–224) 0.68 
Androstenedione (ng/dl)    
 Median (range) 341 (158–1,644) 344 (91–996)  
 Adjusted meana (95% CI) 338 (251–454) 323 (245–426) 0.54 
Testosterone (ng/dl)    
 Median (range) 22.0 (6–187) 20.5 (2–166)  
 Adjusted meana (95% CI) 19.3 (11.4–32.9) 15.7 (9.6–25.9) 0.12 
Estradiol (pg/ml)    
 Median (range) 11,805 (3,332–44,431) 9,510 (402–81,083)  
 Adjusted meana (95% CI) 9,901 (5,468–17,929) 7,526 (4,315–13,124) 0.06 
Estrone (pg/ml)    
 Median (range) 26,356 (4,848–151,824) 30,815 (2,753–147,865)  
 Adjusted meana (95% CI) 27,574 (15,549–48,899) 28,135 (16,451–48,117) 0.89 
Estriol (ng/ml)    
 Median (range) 188 (54–755) 223 (44.7–768)  
 Adjusted meana (95% CI) 276 (174–438) 303 (199–461) 0.43 
HormonePre-eclampsia (N = 86)Uncomplicated pregnancy (N = 86)P
DHEA (ng/dL)    
 Median (range) 454 (124–1,598) 531 (103–1,470)  
 Adjusted meana (95% CIb462 (332–642) 447 (328–609) 0.70 
DHEAS (μg/dl)    
 Median (range) 151 (18–709) 187 (20–885)  
 Adjusted meana (95% CI) 132 (80–220) 139 (87–224) 0.68 
Androstenedione (ng/dl)    
 Median (range) 341 (158–1,644) 344 (91–996)  
 Adjusted meana (95% CI) 338 (251–454) 323 (245–426) 0.54 
Testosterone (ng/dl)    
 Median (range) 22.0 (6–187) 20.5 (2–166)  
 Adjusted meana (95% CI) 19.3 (11.4–32.9) 15.7 (9.6–25.9) 0.12 
Estradiol (pg/ml)    
 Median (range) 11,805 (3,332–44,431) 9,510 (402–81,083)  
 Adjusted meana (95% CI) 9,901 (5,468–17,929) 7,526 (4,315–13,124) 0.06 
Estrone (pg/ml)    
 Median (range) 26,356 (4,848–151,824) 30,815 (2,753–147,865)  
 Adjusted meana (95% CI) 27,574 (15,549–48,899) 28,135 (16,451–48,117) 0.89 
Estriol (ng/ml)    
 Median (range) 188 (54–755) 223 (44.7–768)  
 Adjusted meana (95% CI) 276 (174–438) 303 (199–461) 0.43 
a

Adjusted means are geometric and from models that include a variable representing the individual match, race (white/other), parity (nulliparous, 1, 2+), gravidity (1, 2, 3, 4+), smoking (yes/no), weeks of gestation (continuous) and hours of labor (continuous).

b

CI, confidence interval.

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