Skip to Main Content
Table 3

Relationships of p53 mutations in the highly conserved domains or in the functional/structural domains, and clinicopathological and biological variables of the 160 CRC patients

p53
No mutation (%)Nonconserved (%)Conserved (%)PL3 (%)LSH (%)Outside L3/LSH (%)P
Total 100 (62) 22 (14) 38 (24)      
Site         
 Proximal tumors 26 (84) 3 (10) 2 (6)      
 Distal tumors 74 (57) 19 (15) 36 (28) <0.05     
DNA ploidy         
 Diploid 35 (88) 2 (5) 3 (7)      
 Aneuploid 65 (54) 20 (17) 35 (29) <0.01     
SPF         
 ≤18.3 60 (74) 10 (12) 11 (14)  4 (5) 5 (6) 12 (15)  
 >18.3 40 (51) 12 (15) 27 (34) <0.01 14 (18) 6 (8) 17 (22) <0.05 
p53
No mutation (%)Nonconserved (%)Conserved (%)PL3 (%)LSH (%)Outside L3/LSH (%)P
Total 100 (62) 22 (14) 38 (24)      
Site         
 Proximal tumors 26 (84) 3 (10) 2 (6)      
 Distal tumors 74 (57) 19 (15) 36 (28) <0.05     
DNA ploidy         
 Diploid 35 (88) 2 (5) 3 (7)      
 Aneuploid 65 (54) 20 (17) 35 (29) <0.01     
SPF         
 ≤18.3 60 (74) 10 (12) 11 (14)  4 (5) 5 (6) 12 (15)  
 >18.3 40 (51) 12 (15) 27 (34) <0.01 14 (18) 6 (8) 17 (22) <0.05 
Close Modal

or Create an Account

Close Modal
Close Modal