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Table 2

Univariate analysis of risk factors of appendicular bone sarcoma in a cohort of 683 Rottweiler dogs

Risk FactorDogs with bone sarcomaDogs without bone sarcomaHazard Ratio (95% CI)P
Total no. 86 dogs 597 dogs   
Gender     
 Male 35 dogs 259 dogs 1.00  
 Female 51 dogs 338 dogs 1.01 (0.66–1.55) 0.97 
Neuter status     
 Intact male 10 dogs 120 dogs 1.00  
 Castrated male 25 dogs 139 dogs 1.86 (0.89–3.87) 0.10 
 Intact female  5 dogs  64 dogs 1.00  
 Spayed female 46 dogs 274 dogs 0.95 (0.38–2.40) 0.91 
Lifetime gonadal exposure     
 Months intact (mean± SD)     
  Male 53.1 ± 44.3 mo 71.1 ± 42.7 mo 0.98 (0.98–0.99) <0.0001 
  Female 40.5 ± 34.0 mo 55.6 ± 35.0 mo 0.98 (0.97–0.99) <0.0001 
Body size     
 Adult height (mean± SD)     
  Male 61.0 ± 2.8 cm 65.8 ± 2.8 cm 1.10 (0.97–1.26) 0.15 
  Female 24.0 ± 1.1 cm 61.0 ± 3.3 cm 1.00 (0.91–1.10) 0.97 
 Adult body weight (mean± SD)     
  Male 50.5 ± 7.6 kg 49.7 ± 5.7 kg 1.04 (0.99–1.10) 0.15 
  Female 40.9 ± 4.7 kg 40.6 ± 5.0 kg 1.01 (0.96–1.01) 0.74 
Risk FactorDogs with bone sarcomaDogs without bone sarcomaHazard Ratio (95% CI)P
Total no. 86 dogs 597 dogs   
Gender     
 Male 35 dogs 259 dogs 1.00  
 Female 51 dogs 338 dogs 1.01 (0.66–1.55) 0.97 
Neuter status     
 Intact male 10 dogs 120 dogs 1.00  
 Castrated male 25 dogs 139 dogs 1.86 (0.89–3.87) 0.10 
 Intact female  5 dogs  64 dogs 1.00  
 Spayed female 46 dogs 274 dogs 0.95 (0.38–2.40) 0.91 
Lifetime gonadal exposure     
 Months intact (mean± SD)     
  Male 53.1 ± 44.3 mo 71.1 ± 42.7 mo 0.98 (0.98–0.99) <0.0001 
  Female 40.5 ± 34.0 mo 55.6 ± 35.0 mo 0.98 (0.97–0.99) <0.0001 
Body size     
 Adult height (mean± SD)     
  Male 61.0 ± 2.8 cm 65.8 ± 2.8 cm 1.10 (0.97–1.26) 0.15 
  Female 24.0 ± 1.1 cm 61.0 ± 3.3 cm 1.00 (0.91–1.10) 0.97 
 Adult body weight (mean± SD)     
  Male 50.5 ± 7.6 kg 49.7 ± 5.7 kg 1.04 (0.99–1.10) 0.15 
  Female 40.9 ± 4.7 kg 40.6 ± 5.0 kg 1.01 (0.96–1.01) 0.74 
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