Phenotype-genotype correlation at each quantitative trait locus
| Locus . | Allele . | N . | No. of foci/cm liver area . | % liver area occupied by foci . | Average size (mm)a . | GST-P mRNA . | GGT mRNA . | . | . | . | . | . |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Drh1a | D/D | 22 | 41 ± 20 | 3.4 ± 2.5 | 7.5 ± 2.5 | 2.3 ± 2.9 | 2.2 ± 1.8 | |||||
| D/F | 60 | 86 ± 36]b | 7.8 ± 4.7]b | 8.6 ± 2.9 | 4.4 ± 3.5 | 4.6 ± 3.2]c | ||||||
| F/F | 26 | 99 ± 36 | 8.5 ± 4.6 | 8.0 ± 2.4 | 5.3 ± 3.7 | 5.4 ± 3.9 | ||||||
| Drh1b | D/D | 26 | 46 ± 27 | 3.8 ± 3.0 | 6.7 ± 2.0 | 2.1 ± 2.7 | 2.46 ± 1.74 | |||||
| D/F | 56 | 87 ± 35]b | 7.9 ± 4.7]c | 8.7 ± 2.8 | 4.6 ± 3.5]d | 4.55 ± 3.27]d | ||||||
| F/F | 26 | 99 ± 37 | 8.6 ± 4.6 | 8.7 ± 2.8 | 5.3 ± 3.7 | 5.6 ± 4.0 | ||||||
| Drh1c | D/D | 32 | 60 ± 38 | 4.4 ± 3.2 | 6.8 ± 1.9 | 2.7 ± 3.0 | 2.6 ± 1.9 | |||||
| D/F | 58 | 86 ± 34]d | 7.9 ± 4.5]b | 8.8 ± 2.9]c | 4.7 ± 3.5]d | 4.7 ± 3.5]d | ||||||
| F/F | 18 | 97 ± 43 | 9.2 ± 5.4 | 8.8 ± 2.5 | 5.4 ± 4.1 | 5.7 ± 3.7 | ||||||
| Drh2a | D/D | 36 | 55 ± 31 | 4.2 ± 3.3 | 7.0 ± 2.5 | 2.3 ± 2.1 | 3.1 ± 3.1 | |||||
| D/F | 47 | 87 ± 38]c | 7.4 ± 4.4]c | 8.2 ± 2.4 | 4.5 ± 3.5]c | 4.4 ± 3.1 | ||||||
| F/F | 25 | 103 ± 33 | 10.5 ± 4.4]c | 10.1 ± 2.7]d | 6.4 ± 3.9 | 5.6 ± 3.6 | ||||||
| Drh2b | D/D | 33 | 58 ± 32 | 4.6 ± 3.5 | 7.1 ± 2.4 | 2.5 ± 2.3 | 3.4 ± 3.2 | |||||
| D/F | 53 | 83 ± 37]d | 7.1 ± 4.4]d | 8.1 ± 2.5 | 4.3 ± 3.6 | 4.1 ± 3.1 | ||||||
| F/F | 22 | 106 ± 35 | 10.8 ± 4.6]d | 10.1 ± 2.8]d | 6.6 ± 3.6 | 5.9 ± 3.7 |
| Locus . | Allele . | N . | No. of foci/cm liver area . | % liver area occupied by foci . | Average size (mm)a . | GST-P mRNA . | GGT mRNA . | . | . | . | . | . |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Drh1a | D/D | 22 | 41 ± 20 | 3.4 ± 2.5 | 7.5 ± 2.5 | 2.3 ± 2.9 | 2.2 ± 1.8 | |||||
| D/F | 60 | 86 ± 36]b | 7.8 ± 4.7]b | 8.6 ± 2.9 | 4.4 ± 3.5 | 4.6 ± 3.2]c | ||||||
| F/F | 26 | 99 ± 36 | 8.5 ± 4.6 | 8.0 ± 2.4 | 5.3 ± 3.7 | 5.4 ± 3.9 | ||||||
| Drh1b | D/D | 26 | 46 ± 27 | 3.8 ± 3.0 | 6.7 ± 2.0 | 2.1 ± 2.7 | 2.46 ± 1.74 | |||||
| D/F | 56 | 87 ± 35]b | 7.9 ± 4.7]c | 8.7 ± 2.8 | 4.6 ± 3.5]d | 4.55 ± 3.27]d | ||||||
| F/F | 26 | 99 ± 37 | 8.6 ± 4.6 | 8.7 ± 2.8 | 5.3 ± 3.7 | 5.6 ± 4.0 | ||||||
| Drh1c | D/D | 32 | 60 ± 38 | 4.4 ± 3.2 | 6.8 ± 1.9 | 2.7 ± 3.0 | 2.6 ± 1.9 | |||||
| D/F | 58 | 86 ± 34]d | 7.9 ± 4.5]b | 8.8 ± 2.9]c | 4.7 ± 3.5]d | 4.7 ± 3.5]d | ||||||
| F/F | 18 | 97 ± 43 | 9.2 ± 5.4 | 8.8 ± 2.5 | 5.4 ± 4.1 | 5.7 ± 3.7 | ||||||
| Drh2a | D/D | 36 | 55 ± 31 | 4.2 ± 3.3 | 7.0 ± 2.5 | 2.3 ± 2.1 | 3.1 ± 3.1 | |||||
| D/F | 47 | 87 ± 38]c | 7.4 ± 4.4]c | 8.2 ± 2.4 | 4.5 ± 3.5]c | 4.4 ± 3.1 | ||||||
| F/F | 25 | 103 ± 33 | 10.5 ± 4.4]c | 10.1 ± 2.7]d | 6.4 ± 3.9 | 5.6 ± 3.6 | ||||||
| Drh2b | D/D | 33 | 58 ± 32 | 4.6 ± 3.5 | 7.1 ± 2.4 | 2.5 ± 2.3 | 3.4 ± 3.2 | |||||
| D/F | 53 | 83 ± 37]d | 7.1 ± 4.4]d | 8.1 ± 2.5 | 4.3 ± 3.6 | 4.1 ± 3.1 | ||||||
| F/F | 22 | 106 ± 35 | 10.8 ± 4.6]d | 10.1 ± 2.8]d | 6.6 ± 3.6 | 5.9 ± 3.7 |
Data shown are ×100 original figures.
P < 0.0001.
0.001 > P > 0.0001.
0.01 > P > 0.001.