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Table 1.

Effect of PAR1 Antagonists on Pulmonary M24met Metastasis

AntagonistnPulmonary Tumor Foci, Mean (SD)P*% Inhibition
Experiment 1 None 8 57 (30)   
 ATAP2 + WEDE15 8 28 (25) 0.06 50.4 
 TF9-10H10 4 68 (14) 0.5 0 
Experiment 2 None 8 76 (40)   
 ATAP2 + WEDE15 8 32 (13) <0.05 57.3 
 ATAP2 7 50 (27) 0.2 33.9 
AntagonistnPulmonary Tumor Foci, Mean (SD)P*% Inhibition
Experiment 1 None 8 57 (30)   
 ATAP2 + WEDE15 8 28 (25) 0.06 50.4 
 TF9-10H10 4 68 (14) 0.5 0 
Experiment 2 None 8 76 (40)   
 ATAP2 + WEDE15 8 32 (13) <0.05 57.3 
 ATAP2 7 50 (27) 0.2 33.9 
*

Probability of no difference using the two-tailed t test.

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