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Table 3.

Active Caspase-3 Levels in Tumors Grown in SP+/+ and SP−/− Mice

SP+/+SP−/−
Mean* 27.7 22.6 
SD 15 8.6 
n 49 66 
Min 
Max 76 43 
SP+/+SP−/−
Mean* 27.7 22.6 
SD 15 8.6 
n 49 66 
Min 
Max 76 43 

Note: The number of tumor cells positive for cleaved caspase-3 was counted by three independent observers in PAN02 tumors grown in SP+/+ or SP−/− mice in the number (n) of 200× fields indicated. Min, minimum; Max, maximum number/hpf.

*

P < 0.025, Student's t test.

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