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Table 1.

Expression pattern for β1 integrin, extracellular fibronectin, and laminin-1 in breast cancer

FactorNo. patientsScore, n (%)
0123
β1 integrin intensity 149 32 (21.5) 75 (50.3) 27 (18.1) 15 (10.1) 
β1 integrin percentage 147 31 (21.1) 2 (1.4) 2 (1.4) 112 (76.2) 
ECM FN intensity 134 79 (59.8) 46 (34.8) 7 (5.3) 2 (1.5) 
ECM FN pattern 134 79 (59.8) 8 (6.1) 14 (10.6) 33 (25.0) 
ECM LN intensity 135 92 (68.1) 10 (7.4) 27 (20.0) 6 (4.4) 
ECM LN pattern 135 91 (67.4) 29 (21.5) 6 (4.4) 9 (6.7) 
FactorNo. patientsScore, n (%)
0123
β1 integrin intensity 149 32 (21.5) 75 (50.3) 27 (18.1) 15 (10.1) 
β1 integrin percentage 147 31 (21.1) 2 (1.4) 2 (1.4) 112 (76.2) 
ECM FN intensity 134 79 (59.8) 46 (34.8) 7 (5.3) 2 (1.5) 
ECM FN pattern 134 79 (59.8) 8 (6.1) 14 (10.6) 33 (25.0) 
ECM LN intensity 135 92 (68.1) 10 (7.4) 27 (20.0) 6 (4.4) 
ECM LN pattern 135 91 (67.4) 29 (21.5) 6 (4.4) 9 (6.7) 

NOTE: β1 integrin intensity score (based on membranous signal): 0 = none, 1 = light, 2 = moderate, 3 = heavy; β1 integrin percentage score (based on the percentage of tumor cells stained in the sample): 0 = <10%, 1 = 10% to 25%, 2 = 25% to 50%, 3 = >50%; ECM fibronectin intensity score: 0 = none, 1 = light, 2 = moderate, 3 = heavy; ECM fibronectin pattern score (of extracellular staining): negative = 0, focal (<25%) = 1, moderate (25–75%) = 2, diffuse (>75%) = 3; ECM laminin-1 intensity score: 0 = none, 1 = light, 2 = moderate, 3 = heavy; ECM laminin-1 pattern score (of extracellular staining): negative = 0, focal (<25%) = 1, moderate (25–75%) = 2, diffuse (>75%) = 3.

Abbreviations: FN, fibronectin; LN, laminin-1.

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