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Table 1.

Size of necrosis in infected (2 d p.i.) and uninfected CT26 tumors with and without depletion of neutrophils

TumorBacteriaAnti-Gr1Percentage necrosis
CT26 Not infected − 5–15% 
 S. typhimurium SL7207 − 60–65% 
 S. typhimurium SL7207 75–85% 
 E. coli TOP10 − 60–65% 
 E. coli TOP10 80–85% 
 S. flexneri M90T − 65–70% 
 S. flexneri M90T 85–90% 
TumorBacteriaAnti-Gr1Percentage necrosis
CT26 Not infected − 5–15% 
 S. typhimurium SL7207 − 60–65% 
 S. typhimurium SL7207 75–85% 
 E. coli TOP10 − 60–65% 
 E. coli TOP10 80–85% 
 S. flexneri M90T − 65–70% 
 S. flexneri M90T 85–90% 

NOTE: Percentage of necrosis was determined on paraffin sections after H&E staining by using cell^D software (Olympus).

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