Skip to Main Content
Table 1.

Accepted and candidate human tumor viruses and selected animal model tumor viruses

Virus familyCausal role in human cancer
Animal models
AcceptedPotential
Adenoviridae  Subgroups B, C, D Multiple serotypes 
Flaviviridae HCV   
Hepadnaviridae HBV  WHV, GSHV 
Herpesviridae    
    γ-Herpesviruses EBV, KSHV/HHV-8  HVS, MuγHV 
Papillomaviridae HPV (high-risk types) HPV (other types) CRPV, BPV 
Polyomaviridae  SV40, BKV, JCV, MCPyV SV40, MuPyV 
Retroviridae    
    Simple  XMRV, HERVs, HMTV ALV/ASV, MLV/MSV, FeLV/FeSV, MMTV 
    Complex HTLV-1  BLV 
Virus familyCausal role in human cancer
Animal models
AcceptedPotential
Adenoviridae  Subgroups B, C, D Multiple serotypes 
Flaviviridae HCV   
Hepadnaviridae HBV  WHV, GSHV 
Herpesviridae    
    γ-Herpesviruses EBV, KSHV/HHV-8  HVS, MuγHV 
Papillomaviridae HPV (high-risk types) HPV (other types) CRPV, BPV 
Polyomaviridae  SV40, BKV, JCV, MCPyV SV40, MuPyV 
Retroviridae    
    Simple  XMRV, HERVs, HMTV ALV/ASV, MLV/MSV, FeLV/FeSV, MMTV 
    Complex HTLV-1  BLV 

NOTE: Adapted from J. Butel (57).

Abbreviations: ALV/ASV, avian leukosis-sarcoma virus group; BLV, bovine leukemia virus; BKV, BK virus; BPV, bovine papillomavirus; FeLV/FeSV, feline leukemia-sarcoma virus group; GSHV, ground squirrel hepatitis virus; HERVs, human endogenous retroviruses; HMTV, human mammary tumor virus; HVS, herpesvirus saimiri; JCV, JC virus; MCPyV, Merkel cell polyomavirus; MLV/MSV, murine leukemia-sarcoma virus group; MMTV, mouse mammary tumor virus; MuγHV, murine γ-herpesvirus; MuPyV, murine polyoma virus; WHV, woodchuck hepatitis virus; XMRV, xenotropic murine leukemia virus–related virus.

Close Modal

or Create an Account

Close Modal
Close Modal