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Table 1.

MiRNAs dysregulated in stage II colon cancer

MiRNARegulation*Fold (log 2)
Normal vs MSI comparison   
    hsa-miR-145 Down −1.9 
    hsa-miR-455 Down −1.3 
    hsa-miR-484 Down −1.2 
    hsa-miR-101 Down −1.0 
    hsa-miR-492 Up 1.2 
    hsa-miR-20a Up 1.1 
    hsa-miR-432* Up 1.1 
    hsa-miR-21 Up 1.0 
Normal vs MSS comparison   
    hsa-miR-142-3p Down −2.4 
    hsa-miR-212 Down −2.3 
    hsa-miR-146b Down −1.9 
    hsa-miR-217 Down −1.7 
    hsa-miR-20a Up 1.6 
    hsa-miR-510 Up 1.5 
    hsa-miR-92 Up 1.3 
    hsa-miR-513 Up 1.2 
MSS vs MSI comparison   
    hsa-miR-212 Down −2.3 
    hsa-miR-142-3p Down −2.1 
    hsa-miR-144 Down −1.5 
    hsa-miR-151 Down −1.4 
MiRNAs dysregulated in both MSI and MSS   
    hsa-miR-145 Down −1.7 
    hsa-miR-455 Down −1.4 
    hsa-miR-484 Down −1.2 
    hsa-miR-101 Down −1.1 
    hsa-miR-20a Up 1.4 
    hsa-miR-510 Up 1.3 
    hsa-miR-92 Up 1.0 
    hsa-miR-513 Up 1.0 
Recurrence vs nonrecurrence comparison (MSS only)   
    hsa-let-7d Up 0.7 
    hsa-let-7b Up 0.7 
    hsa-miR-126 Up 0.5 
    hsa-miR-1 Up 0.5 
    hsa-miR-320 Down −1.1 
    hsa-miR-498 Down −0.7 
    hsa-miR-492 Down −0.7 
    hsa-miR-526c Down −0.7 
MiRNARegulation*Fold (log 2)
Normal vs MSI comparison   
    hsa-miR-145 Down −1.9 
    hsa-miR-455 Down −1.3 
    hsa-miR-484 Down −1.2 
    hsa-miR-101 Down −1.0 
    hsa-miR-492 Up 1.2 
    hsa-miR-20a Up 1.1 
    hsa-miR-432* Up 1.1 
    hsa-miR-21 Up 1.0 
Normal vs MSS comparison   
    hsa-miR-142-3p Down −2.4 
    hsa-miR-212 Down −2.3 
    hsa-miR-146b Down −1.9 
    hsa-miR-217 Down −1.7 
    hsa-miR-20a Up 1.6 
    hsa-miR-510 Up 1.5 
    hsa-miR-92 Up 1.3 
    hsa-miR-513 Up 1.2 
MSS vs MSI comparison   
    hsa-miR-212 Down −2.3 
    hsa-miR-142-3p Down −2.1 
    hsa-miR-144 Down −1.5 
    hsa-miR-151 Down −1.4 
MiRNAs dysregulated in both MSI and MSS   
    hsa-miR-145 Down −1.7 
    hsa-miR-455 Down −1.4 
    hsa-miR-484 Down −1.2 
    hsa-miR-101 Down −1.1 
    hsa-miR-20a Up 1.4 
    hsa-miR-510 Up 1.3 
    hsa-miR-92 Up 1.0 
    hsa-miR-513 Up 1.0 
Recurrence vs nonrecurrence comparison (MSS only)   
    hsa-let-7d Up 0.7 
    hsa-let-7b Up 0.7 
    hsa-miR-126 Up 0.5 
    hsa-miR-1 Up 0.5 
    hsa-miR-320 Down −1.1 
    hsa-miR-498 Down −0.7 
    hsa-miR-492 Down −0.7 
    hsa-miR-526c Down −0.7 
*

Up- or down-regulation is stated as miRNA expression in cancer relative to normal, recurrence relative to nonrecurrence, or MSS relative to MSI.

Median log2 fold change between the two groups compared.

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