Hazard ratios and 95% confidence intervals for clearance of incident transient and persistent high-risk HPV infection by levels of circulating plasma micronutrients
| Micronutrient/quartile . | Quartile range (ng/mL) . | Transient infections (first 120 d since detection) . | . | . | Persistent infections (after 120 d of detection) . | . | . | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| . | . | No. cleared/infections (mo)* . | Hazard ratio† (95% confidence limits) . | Ptrend‡ . | No. cleared/infections (mo)* . | Hazard ratio† (95% confidence limits) . | Ptrend‡ . | |||||||
| Trans-lutein | ||||||||||||||
| Low | 41.87-106.63 | 6/249 | 1.00 | 27/290 | 1.00 | |||||||||
| 2 | 106.64-156.70 | 6/248 | 0.93 (0.28–3.12) | 28/308 | 1.40 (0.84–2.36) | |||||||||
| 3 | 156.71-225.21 | 13/213 | 3.03 (1.20–7.70) | 18/226 | 0.93 (0.52–1.68) | |||||||||
| High | 225.22-624.18 | 7/249 | 1.74 (0.50–5.99) | 0.33 | 28/282 | 1.40 (0.82–2.36) | 0.38 | |||||||
| Trans-zeaxanthin | ||||||||||||||
| Low | 20.28-46.40 | 6/245 | 1.00 | 29/290 | 1.00 | |||||||||
| 2 | 46.41-58.22 | 8/254 | 1.99 (0.67–5.87) | 22/279 | 0.71 (0.43–1.18) | |||||||||
| 3 | 58.23-82.69 | 10/232 | 3.24 (1.02–10.28) | 19/253 | 0.58 (0.32–1.08) | |||||||||
| High | 82.70-281.10 | 8/229 | 2.18 (0.52–9.17) | 0.36 | 31/283 | 1.27 (0.73–2.22) | 0.17 | |||||||
| Total trans-lutein/zeaxanthin | ||||||||||||||
| Low | 73.53-158.68 | 4/242 | 1.00 | 31/311 | 1.00 | |||||||||
| 2 | 158.69-212.03 | 6/252 | 1.08 (0.27–4.34) | 23/266 | 1.09 (0.63–1.87) | |||||||||
| 3 | 212.04-303.92 | 13/229 | 4.75 (1.62–13.89) | 18/254 | 0.73 (0.39–1.35) | |||||||||
| High | 303.93-905.29 | 9/237 | 3.15 (1.04–9.53) | 0.03 | 23/275 | 1.26 (0.75–2.11) | 0.42 | |||||||
| Total cis-lutein/zeaxanthin and trans-lutein/zeaxanthin | ||||||||||||||
| Low | 112.67-259.20 | 4/252 | 1.00 | 33/310 | 1.00 | |||||||||
| 2 | 259.21-332.78 | 8/238 | 1.80 (0.59–5.51) | 17/266 | 0.88 (0.50–1.56) | |||||||||
| 3 | 332.79-452.23 | 12/232 | 4.53 (1.32–15.54) | 26/267 | 1.15 (0.65–2.04) | |||||||||
| High | 452.24-1,287.6 | 8/239 | 3.05 (0.87–10.74) | 0.11 | 25/262 | 1.11 (0.63–1.93) | 0.60 | |||||||
| α-Cryptoxanthin | ||||||||||||||
| Low | 0.33-33.52 | 6/219 | 1.00 | 31/296 | 1.00 | |||||||||
| 2 | 33.53-43.53 | 5/242 | 0.83 (0.24–2.82) | 28/312 | 0.71 (0.41–1.21) | |||||||||
| 3 | 43.54-54.44 | 10/251 | 1.81 (0.65–5.05) | 18/239 | 0.84 (0.43–1.65) | |||||||||
| High | 54.45-106.45 | 11/248 | 1.97 (0.76–5.10) | 0.06 | 24/258 | 0.73 (0.39–1.37) | 0.54 | |||||||
| β-Cryptoxanthin | ||||||||||||||
| Low | 17.54-113.85 | 5/237 | 1.00 | 29/306 | 1.00 | |||||||||
| 2 | 113.86-158.65 | 6/244 | 1.31 (0.34–5.10) | 29/301 | 0.85 (0.52–1.38) | |||||||||
| 3 | 158.66-242.59 | 7/234 | 1.78 (0.51–6.17) | 22/267 | 0.86 (0.50–1.46) | |||||||||
| High | 242.60-1,114.6 | 14/245 | 4.65 (1.65–13.09) | 0.003 | 21/231 | 0.94 (0.51–1.73) | 0.97 | |||||||
| Total cryptoxanthin | ||||||||||||||
| Low | 17.87-148.75 | 6/235 | 1.00 | 27/295 | 1.00 | |||||||||
| 2 | 148.76-207.65 | 5/245 | 0.87 (0.20–3.75) | 30/306 | 0.91 (0.54–1.53) | |||||||||
| 3 | 207.66-296.12 | 7/237 | 1.46 (0.44–4.85) | 23/274 | 0.99 (0.57–1.71) | |||||||||
| High | 296.13-1,164.6 | 14/244 | 3.47 (1.36–8.87) | 0.003 | 21/230 | 1.02 (0.54–1.94) | 0.84 | |||||||
| Total trans-lycopene and cis-lycopene | ||||||||||||||
| Low | 0.00-29.49 | 3/241 | 1.00 | 28/312 | 1.00 | |||||||||
| 2 | 29.50-42.89 | 10/239 | 2.44 (0.51–11.75) | 26/277 | 0.99 (0.60–1.64) | |||||||||
| 3 | 42.90-59.30 | 4/241 | 1.51 (0.27–8.34) | 27/300 | 1.15 (0.70–1.88) | |||||||||
| High | 59.31-245.11 | 15/238 | 7.03 (1.61–30.70) | 0.004 | 20/216 | 1.14 (0.64–2.02) | 0.57 | |||||||
| Total lycopene | ||||||||||||||
| Low | 55.96-251.67 | 9/236 | 1.00 | 25/258 | 1.00 | |||||||||
| 2 | 251.68-337.62 | 9/213 | 1.28 (0.42–3.91) | 25/267 | 1.03 (0.60–1.74) | |||||||||
| 3 | 337.63-449.99 | 7/262 | 0.50 (0.16–1.54) | 29/296 | 1.16 (0.71–1.89) | |||||||||
| High | 450.00-941.04 | 7/249 | 0.61 (0.18–2.09) | 0.32 | 22/285 | 0.60 (0.35–1.04) | 0.07 | |||||||
| α-Carotene | ||||||||||||||
| Low | 0.07-26.81 | 6/246 | 1.00 | 26/305 | 1.00 | |||||||||
| 2 | 26.82-46.00 | 8/248 | 1.16 (0.45–2.98) | 25/297 | 0.76 (0.44–1.29) | |||||||||
| 3 | 46.01-68.81 | 4/225 | 0.84 (0.20–3.51) | 26/270 | 0.91 (0.49–1.72) | |||||||||
| High | 68.82-388.36 | 14/241 | 3.02 (1.07–8.53) | 0.02 | 24/233 | 1.27 (0.67–2.39) | 0.25 | |||||||
| Trans-β-carotene | ||||||||||||||
| Low | 1.87-86.14 | 7/245 | 1.00 | 28/296 | 1.00 | |||||||||
| 2 | 86.15-160.90 | 5/229 | 0.79 (0.25–2.46) | 22/280 | 0.85 (0.47–1.52) | |||||||||
| 3 | 160.91-252.15 | 6/268 | 0.49 (0.14–1.76) | 28/292 | 1.34 (0.79–2.28) | |||||||||
| High | 252.16-1,405.5 | 14/218 | 3.52 (1.44–8.62) | 0.008 | 23/238 | 1.43 (0.76–2.69) | 0.11 | |||||||
| Cis-β-carotene | ||||||||||||||
| Low | 0.00-7.78 | 5/249 | 1.00 | 33/304 | 1.00 | |||||||||
| 2 | 7.79-14.76 | 8/224 | 1.31 (0.37–4.65) | 17/271 | 0.74 (0.40–1.39) | |||||||||
| 3 | 14.77-23.95 | 8/258 | 1.22 (0.31–4.88) | 25/279 | 1.03 (0.60–1.77) | |||||||||
| High | 23.96-97.36 | 11/228 | 3.43 (1.18–9.93) | 0.03 | 26/252 | 1.63 (0.90–2.95) | 0.04 | |||||||
| Total β-carotene | ||||||||||||||
| Low | 2.53-96.54 | 6/242 | 1.00 | 30/300 | 1.00 | |||||||||
| 2 | 96.55-172.86 | 5/239 | 0.90 (0.29–2.77) | 22/286 | 0.82 (0.46–1.46) | |||||||||
| 3 | 172.87-281.15 | 8/259 | 0.88 (0.27–2.92) | 26/278 | 1.23 (0.72–2.08) | |||||||||
| High | 281.16-1,496.4 | 13/220 | 3.79 (1.59–9.00) | 0.005 | 23/242 | 1.31 (0.70–2.47) | 0.19 | |||||||
| Total carotene | ||||||||||||||
| Low | 2.60-127.16 | 6/247 | 1.00 | 29/295 | 1.00 | |||||||||
| 2 | 127.17-225.29 | 5/213 | 1.08 (0.35–3.32) | 22/294 | 0.86 (0.49–1.50) | |||||||||
| 3 | 225.30-379.95 | 7/272 | 0.82 (0.25–2.66) | 25/281 | 1.15 (0.67–1.99) | |||||||||
| High | 379.96-1,724.4 | 14/228 | 3.72 (1.50–9.23) | 0.007 | 25/236 | 1.56 (0.82–2.96) | 0.08 | |||||||
| Total carotenoids | ||||||||||||||
| Low | 198.91-983.25 | 5/229 | 1.00 | 27/283 | 1.00 | |||||||||
| 2 | 983.26-1,329.3 | 10/256 | 1.70 (0.44–6.51) | 24/302 | 1.01 (0.58–1.75) | |||||||||
| 3 | 1,329.4-1,755.8 | 6/242 | 1.42 (0.36–5.55) | 27/271 | 1.12 (0.62–2.02) | |||||||||
| High | 1,755.9-3,979.0 | 11/233 | 2.73 (0.79–9.38) | 0.11 | 23/248 | 1.29 (0.69–2.43) | 0.36 | |||||||
| Retinol | ||||||||||||||
| Low | 0.00-569.45 | 9/284 | 1.00 | 26/279 | 1.00 | |||||||||
| 2 | 569.46-719.20 | 10/244 | 0.91 (0.32–2.60) | 21/231 | 1.04 (0.56–1.92) | |||||||||
| 3 | 719.21-865.26 | 8/224 | 1.03 (0.36–2.92) | 29/282 | 0.87 (0.52–1.44) | |||||||||
| High | 865.27-1,624.2 | 5/208 | 0.86 (0.22–3.41) | 0.87 | 25/314 | 0.65 (0.40–1.07) | 0.051 | |||||||
| α-Tocopherol | ||||||||||||||
| Low | 3,490.4-7,536.0 | 9/269 | 1.00 | 30/296 | 1.00 | |||||||||
| 2 | 7,536.1-9,391.3 | 6/231 | 1.05 (0.31–3.56) | 27/253 | 1.01 (0.55–1.86) | |||||||||
| 3 | 9,391.4-12,375 | 5/288 | 0.74 (0.24–2.29) | 20/295 | 0.80 (0.46–1.39) | |||||||||
| High | 12,376-36,621 | 12/171 | 3.48 (1.33–9.11) | 0.02 | 24/262 | 1.18 (0.60–2.33) | 0.68 | |||||||
| β-Tocopherol and γ-tocopherol | ||||||||||||||
| Low | 29.80-643.85 | 8/244 | 1.00 | 28/292 | 1.00 | |||||||||
| 2 | 643.86-1,073.0 | 11/228 | 1.43 (0.46–4.43) | 22/277 | 0.66 (0.37–1.19) | |||||||||
| 3 | 1,073.1-1,573.6 | 4/246 | 0.34 (0.08–1.51) | 28/275 | 0.83 (0.47–1.47) | |||||||||
| High | 1,573.7-3,564.0 | 9/241 | 0.98 (0.33–2.95) | 0.56 | 23/261 | 0.88 (0.51–1.52) | 0.89 | |||||||
| δ-Tocopherol | ||||||||||||||
| Low | 24.28-165.59 | 9/251 | 1.00 | 23/258 | 1.00 | |||||||||
| 2 | 165.60-243.57 | 9/225 | 1.41 (0.38–5.31) | 23/297 | 0.78 (0.44–1.38) | |||||||||
| 3 | 243.58-417.73 | 7/246 | 1.04 (0.29–3.78) | 29/271 | 1.02 (0.56–1.85) | |||||||||
| High | 417.74-1,090.3 | 7/237 | 1.05 (0.29–3.79) | 0.88 | 26/280 | 1.01 (0.56–1.82) | 0.66 | |||||||
| Total tocopherol | ||||||||||||||
| Low | 4,528.2-9,336.0 | 8/258 | 1.00 | 29/292 | 1.00 | |||||||||
| 2 | 9,336.1-10,885 | 7/236 | 1.19 (0.39–3.68) | 27/264 | 1.03 (0.54–1.96) | |||||||||
| 3 | 10,886-13,604 | 6/289 | 0.96 (0.35–2.68) | 19/274 | 0.88 (0.45–1.71) | |||||||||
| High | 13,605-37,092 | 11/178 | 3.25 (1.21–8.71) | 0.03 | 26/276 | 1.32 (0.69–2.50) | 0.37 | |||||||
| Micronutrient/quartile . | Quartile range (ng/mL) . | Transient infections (first 120 d since detection) . | . | . | Persistent infections (after 120 d of detection) . | . | . | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| . | . | No. cleared/infections (mo)* . | Hazard ratio† (95% confidence limits) . | Ptrend‡ . | No. cleared/infections (mo)* . | Hazard ratio† (95% confidence limits) . | Ptrend‡ . | |||||||
| Trans-lutein | ||||||||||||||
| Low | 41.87-106.63 | 6/249 | 1.00 | 27/290 | 1.00 | |||||||||
| 2 | 106.64-156.70 | 6/248 | 0.93 (0.28–3.12) | 28/308 | 1.40 (0.84–2.36) | |||||||||
| 3 | 156.71-225.21 | 13/213 | 3.03 (1.20–7.70) | 18/226 | 0.93 (0.52–1.68) | |||||||||
| High | 225.22-624.18 | 7/249 | 1.74 (0.50–5.99) | 0.33 | 28/282 | 1.40 (0.82–2.36) | 0.38 | |||||||
| Trans-zeaxanthin | ||||||||||||||
| Low | 20.28-46.40 | 6/245 | 1.00 | 29/290 | 1.00 | |||||||||
| 2 | 46.41-58.22 | 8/254 | 1.99 (0.67–5.87) | 22/279 | 0.71 (0.43–1.18) | |||||||||
| 3 | 58.23-82.69 | 10/232 | 3.24 (1.02–10.28) | 19/253 | 0.58 (0.32–1.08) | |||||||||
| High | 82.70-281.10 | 8/229 | 2.18 (0.52–9.17) | 0.36 | 31/283 | 1.27 (0.73–2.22) | 0.17 | |||||||
| Total trans-lutein/zeaxanthin | ||||||||||||||
| Low | 73.53-158.68 | 4/242 | 1.00 | 31/311 | 1.00 | |||||||||
| 2 | 158.69-212.03 | 6/252 | 1.08 (0.27–4.34) | 23/266 | 1.09 (0.63–1.87) | |||||||||
| 3 | 212.04-303.92 | 13/229 | 4.75 (1.62–13.89) | 18/254 | 0.73 (0.39–1.35) | |||||||||
| High | 303.93-905.29 | 9/237 | 3.15 (1.04–9.53) | 0.03 | 23/275 | 1.26 (0.75–2.11) | 0.42 | |||||||
| Total cis-lutein/zeaxanthin and trans-lutein/zeaxanthin | ||||||||||||||
| Low | 112.67-259.20 | 4/252 | 1.00 | 33/310 | 1.00 | |||||||||
| 2 | 259.21-332.78 | 8/238 | 1.80 (0.59–5.51) | 17/266 | 0.88 (0.50–1.56) | |||||||||
| 3 | 332.79-452.23 | 12/232 | 4.53 (1.32–15.54) | 26/267 | 1.15 (0.65–2.04) | |||||||||
| High | 452.24-1,287.6 | 8/239 | 3.05 (0.87–10.74) | 0.11 | 25/262 | 1.11 (0.63–1.93) | 0.60 | |||||||
| α-Cryptoxanthin | ||||||||||||||
| Low | 0.33-33.52 | 6/219 | 1.00 | 31/296 | 1.00 | |||||||||
| 2 | 33.53-43.53 | 5/242 | 0.83 (0.24–2.82) | 28/312 | 0.71 (0.41–1.21) | |||||||||
| 3 | 43.54-54.44 | 10/251 | 1.81 (0.65–5.05) | 18/239 | 0.84 (0.43–1.65) | |||||||||
| High | 54.45-106.45 | 11/248 | 1.97 (0.76–5.10) | 0.06 | 24/258 | 0.73 (0.39–1.37) | 0.54 | |||||||
| β-Cryptoxanthin | ||||||||||||||
| Low | 17.54-113.85 | 5/237 | 1.00 | 29/306 | 1.00 | |||||||||
| 2 | 113.86-158.65 | 6/244 | 1.31 (0.34–5.10) | 29/301 | 0.85 (0.52–1.38) | |||||||||
| 3 | 158.66-242.59 | 7/234 | 1.78 (0.51–6.17) | 22/267 | 0.86 (0.50–1.46) | |||||||||
| High | 242.60-1,114.6 | 14/245 | 4.65 (1.65–13.09) | 0.003 | 21/231 | 0.94 (0.51–1.73) | 0.97 | |||||||
| Total cryptoxanthin | ||||||||||||||
| Low | 17.87-148.75 | 6/235 | 1.00 | 27/295 | 1.00 | |||||||||
| 2 | 148.76-207.65 | 5/245 | 0.87 (0.20–3.75) | 30/306 | 0.91 (0.54–1.53) | |||||||||
| 3 | 207.66-296.12 | 7/237 | 1.46 (0.44–4.85) | 23/274 | 0.99 (0.57–1.71) | |||||||||
| High | 296.13-1,164.6 | 14/244 | 3.47 (1.36–8.87) | 0.003 | 21/230 | 1.02 (0.54–1.94) | 0.84 | |||||||
| Total trans-lycopene and cis-lycopene | ||||||||||||||
| Low | 0.00-29.49 | 3/241 | 1.00 | 28/312 | 1.00 | |||||||||
| 2 | 29.50-42.89 | 10/239 | 2.44 (0.51–11.75) | 26/277 | 0.99 (0.60–1.64) | |||||||||
| 3 | 42.90-59.30 | 4/241 | 1.51 (0.27–8.34) | 27/300 | 1.15 (0.70–1.88) | |||||||||
| High | 59.31-245.11 | 15/238 | 7.03 (1.61–30.70) | 0.004 | 20/216 | 1.14 (0.64–2.02) | 0.57 | |||||||
| Total lycopene | ||||||||||||||
| Low | 55.96-251.67 | 9/236 | 1.00 | 25/258 | 1.00 | |||||||||
| 2 | 251.68-337.62 | 9/213 | 1.28 (0.42–3.91) | 25/267 | 1.03 (0.60–1.74) | |||||||||
| 3 | 337.63-449.99 | 7/262 | 0.50 (0.16–1.54) | 29/296 | 1.16 (0.71–1.89) | |||||||||
| High | 450.00-941.04 | 7/249 | 0.61 (0.18–2.09) | 0.32 | 22/285 | 0.60 (0.35–1.04) | 0.07 | |||||||
| α-Carotene | ||||||||||||||
| Low | 0.07-26.81 | 6/246 | 1.00 | 26/305 | 1.00 | |||||||||
| 2 | 26.82-46.00 | 8/248 | 1.16 (0.45–2.98) | 25/297 | 0.76 (0.44–1.29) | |||||||||
| 3 | 46.01-68.81 | 4/225 | 0.84 (0.20–3.51) | 26/270 | 0.91 (0.49–1.72) | |||||||||
| High | 68.82-388.36 | 14/241 | 3.02 (1.07–8.53) | 0.02 | 24/233 | 1.27 (0.67–2.39) | 0.25 | |||||||
| Trans-β-carotene | ||||||||||||||
| Low | 1.87-86.14 | 7/245 | 1.00 | 28/296 | 1.00 | |||||||||
| 2 | 86.15-160.90 | 5/229 | 0.79 (0.25–2.46) | 22/280 | 0.85 (0.47–1.52) | |||||||||
| 3 | 160.91-252.15 | 6/268 | 0.49 (0.14–1.76) | 28/292 | 1.34 (0.79–2.28) | |||||||||
| High | 252.16-1,405.5 | 14/218 | 3.52 (1.44–8.62) | 0.008 | 23/238 | 1.43 (0.76–2.69) | 0.11 | |||||||
| Cis-β-carotene | ||||||||||||||
| Low | 0.00-7.78 | 5/249 | 1.00 | 33/304 | 1.00 | |||||||||
| 2 | 7.79-14.76 | 8/224 | 1.31 (0.37–4.65) | 17/271 | 0.74 (0.40–1.39) | |||||||||
| 3 | 14.77-23.95 | 8/258 | 1.22 (0.31–4.88) | 25/279 | 1.03 (0.60–1.77) | |||||||||
| High | 23.96-97.36 | 11/228 | 3.43 (1.18–9.93) | 0.03 | 26/252 | 1.63 (0.90–2.95) | 0.04 | |||||||
| Total β-carotene | ||||||||||||||
| Low | 2.53-96.54 | 6/242 | 1.00 | 30/300 | 1.00 | |||||||||
| 2 | 96.55-172.86 | 5/239 | 0.90 (0.29–2.77) | 22/286 | 0.82 (0.46–1.46) | |||||||||
| 3 | 172.87-281.15 | 8/259 | 0.88 (0.27–2.92) | 26/278 | 1.23 (0.72–2.08) | |||||||||
| High | 281.16-1,496.4 | 13/220 | 3.79 (1.59–9.00) | 0.005 | 23/242 | 1.31 (0.70–2.47) | 0.19 | |||||||
| Total carotene | ||||||||||||||
| Low | 2.60-127.16 | 6/247 | 1.00 | 29/295 | 1.00 | |||||||||
| 2 | 127.17-225.29 | 5/213 | 1.08 (0.35–3.32) | 22/294 | 0.86 (0.49–1.50) | |||||||||
| 3 | 225.30-379.95 | 7/272 | 0.82 (0.25–2.66) | 25/281 | 1.15 (0.67–1.99) | |||||||||
| High | 379.96-1,724.4 | 14/228 | 3.72 (1.50–9.23) | 0.007 | 25/236 | 1.56 (0.82–2.96) | 0.08 | |||||||
| Total carotenoids | ||||||||||||||
| Low | 198.91-983.25 | 5/229 | 1.00 | 27/283 | 1.00 | |||||||||
| 2 | 983.26-1,329.3 | 10/256 | 1.70 (0.44–6.51) | 24/302 | 1.01 (0.58–1.75) | |||||||||
| 3 | 1,329.4-1,755.8 | 6/242 | 1.42 (0.36–5.55) | 27/271 | 1.12 (0.62–2.02) | |||||||||
| High | 1,755.9-3,979.0 | 11/233 | 2.73 (0.79–9.38) | 0.11 | 23/248 | 1.29 (0.69–2.43) | 0.36 | |||||||
| Retinol | ||||||||||||||
| Low | 0.00-569.45 | 9/284 | 1.00 | 26/279 | 1.00 | |||||||||
| 2 | 569.46-719.20 | 10/244 | 0.91 (0.32–2.60) | 21/231 | 1.04 (0.56–1.92) | |||||||||
| 3 | 719.21-865.26 | 8/224 | 1.03 (0.36–2.92) | 29/282 | 0.87 (0.52–1.44) | |||||||||
| High | 865.27-1,624.2 | 5/208 | 0.86 (0.22–3.41) | 0.87 | 25/314 | 0.65 (0.40–1.07) | 0.051 | |||||||
| α-Tocopherol | ||||||||||||||
| Low | 3,490.4-7,536.0 | 9/269 | 1.00 | 30/296 | 1.00 | |||||||||
| 2 | 7,536.1-9,391.3 | 6/231 | 1.05 (0.31–3.56) | 27/253 | 1.01 (0.55–1.86) | |||||||||
| 3 | 9,391.4-12,375 | 5/288 | 0.74 (0.24–2.29) | 20/295 | 0.80 (0.46–1.39) | |||||||||
| High | 12,376-36,621 | 12/171 | 3.48 (1.33–9.11) | 0.02 | 24/262 | 1.18 (0.60–2.33) | 0.68 | |||||||
| β-Tocopherol and γ-tocopherol | ||||||||||||||
| Low | 29.80-643.85 | 8/244 | 1.00 | 28/292 | 1.00 | |||||||||
| 2 | 643.86-1,073.0 | 11/228 | 1.43 (0.46–4.43) | 22/277 | 0.66 (0.37–1.19) | |||||||||
| 3 | 1,073.1-1,573.6 | 4/246 | 0.34 (0.08–1.51) | 28/275 | 0.83 (0.47–1.47) | |||||||||
| High | 1,573.7-3,564.0 | 9/241 | 0.98 (0.33–2.95) | 0.56 | 23/261 | 0.88 (0.51–1.52) | 0.89 | |||||||
| δ-Tocopherol | ||||||||||||||
| Low | 24.28-165.59 | 9/251 | 1.00 | 23/258 | 1.00 | |||||||||
| 2 | 165.60-243.57 | 9/225 | 1.41 (0.38–5.31) | 23/297 | 0.78 (0.44–1.38) | |||||||||
| 3 | 243.58-417.73 | 7/246 | 1.04 (0.29–3.78) | 29/271 | 1.02 (0.56–1.85) | |||||||||
| High | 417.74-1,090.3 | 7/237 | 1.05 (0.29–3.79) | 0.88 | 26/280 | 1.01 (0.56–1.82) | 0.66 | |||||||
| Total tocopherol | ||||||||||||||
| Low | 4,528.2-9,336.0 | 8/258 | 1.00 | 29/292 | 1.00 | |||||||||
| 2 | 9,336.1-10,885 | 7/236 | 1.19 (0.39–3.68) | 27/264 | 1.03 (0.54–1.96) | |||||||||
| 3 | 10,886-13,604 | 6/289 | 0.96 (0.35–2.68) | 19/274 | 0.88 (0.45–1.71) | |||||||||
| High | 13,605-37,092 | 11/178 | 3.25 (1.21–8.71) | 0.03 | 26/276 | 1.32 (0.69–2.50) | 0.37 | |||||||
Cumulative infection length in months, from first positive to first negative visit.
Adjusted for age at first visit, current tobacco smoking status, number of lifetime sexual partners, age at first sex, blood frozen over 1 y indicator variable, coinfection status.
The P for trend is based on a Wald statistic for a trend variable assigned the median for the appropriate quartile.