Osterix expression suppressed osteolysis and lung metastasesl
| Study group* . | Osteolytic lesion incidence (%) . | Bone lysis . | Lung metastases incidence (micro and macro; %) . |
|---|---|---|---|
| K7M2 | 65 | 2.2 | 60 |
| K7M2-neo | 54 | 2.4 | 68 |
| K7M2-osx-1 | 10† | 0.3‡ | 30§ |
| K7M2-osx-2 | 18a | 0.4b | 35c |
| Study group* . | Osteolytic lesion incidence (%) . | Bone lysis . | Lung metastases incidence (micro and macro; %) . |
|---|---|---|---|
| K7M2 | 65 | 2.2 | 60 |
| K7M2-neo | 54 | 2.4 | 68 |
| K7M2-osx-1 | 10† | 0.3‡ | 30§ |
| K7M2-osx-2 | 18a | 0.4b | 35c |
K7M2, K7M2-neo, K7M2-osx-1, and K7M2-osx-2 cells were injected into the left tibia of BALB/c mice. The mice (10 per group) were sacrificed 35 days after tumor cell injection. Results are one representative experiment of two.
P < 0.05 compared with control groups.
P < 0.01 compared with control groups.
P < 0.05 compared with control groups.
P < 0.05 compared with control groups.
P < 0.01 compared with control groups.
P < 0.05 compared with control groups.