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Table 1.

Osterix expression suppressed osteolysis and lung metastasesl

Study group*Osteolytic lesion incidence (%)Bone lysisLung metastases incidence (micro and macro; %)
K7M2 65 2.2 60 
K7M2-neo 54 2.4 68 
K7M2-osx-1 10 0.3 30§ 
K7M2-osx-2 18a 0.4b 35c 
Study group*Osteolytic lesion incidence (%)Bone lysisLung metastases incidence (micro and macro; %)
K7M2 65 2.2 60 
K7M2-neo 54 2.4 68 
K7M2-osx-1 10 0.3 30§ 
K7M2-osx-2 18a 0.4b 35c 
*

K7M2, K7M2-neo, K7M2-osx-1, and K7M2-osx-2 cells were injected into the left tibia of BALB/c mice. The mice (10 per group) were sacrificed 35 days after tumor cell injection. Results are one representative experiment of two.

P < 0.05 compared with control groups.

P < 0.01 compared with control groups.

§

P < 0.05 compared with control groups.

P < 0.05 compared with control groups.

P < 0.01 compared with control groups.

**

P < 0.05 compared with control groups.

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