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Table 2.

Biodistribution of 125I-B72.3 in LS174T-bearing mice treated with STI571 or PBS according to the schedule shown in Table 1 

PBS 120 h (n = 8), average (SD)STI571 120 h (n = 11), average (SD)
Blood 1.38 (0.42) 4.45 (0.34) 
Liver 0.79 (0.26) 1.58 (0.14) 
Spleen 0.70 (0.19) 1.20 (0.11) 
Heart 0.29 (0.08) 0.93 (0.08) 
Lungs 0.66 (0.22) 2.03 (0.16) 
Kidneys 0.46 (0.09) 0.91 (0.08) 
Intestine 0.15 (0.04) 0.48 (0.04) 
Muscle 0.17 (0.08) 0.38 (0.04) 
Bone 0.19 (0.06) 0.58 (0.06) 
Skin 0.42 (0.14) 1.23 (0.12) 
Tumor 9.43 (2.53) 23.18 (2.48) 
PBS 120 h (n = 8), average (SD)STI571 120 h (n = 11), average (SD)
Blood 1.38 (0.42) 4.45 (0.34) 
Liver 0.79 (0.26) 1.58 (0.14) 
Spleen 0.70 (0.19) 1.20 (0.11) 
Heart 0.29 (0.08) 0.93 (0.08) 
Lungs 0.66 (0.22) 2.03 (0.16) 
Kidneys 0.46 (0.09) 0.91 (0.08) 
Intestine 0.15 (0.04) 0.48 (0.04) 
Muscle 0.17 (0.08) 0.38 (0.04) 
Bone 0.19 (0.06) 0.58 (0.06) 
Skin 0.42 (0.14) 1.23 (0.12) 
Tumor 9.43 (2.53) 23.18 (2.48) 
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