Biodistribution of 125I-B72.3 in LS174T-bearing mice treated with STI571 or PBS according to the schedule shown in Table 1
| . | PBS 120 h (n = 8), average (SD) . | STI571 120 h (n = 11), average (SD) . |
|---|---|---|
| Blood | 1.38 (0.42) | 4.45 (0.34) |
| Liver | 0.79 (0.26) | 1.58 (0.14) |
| Spleen | 0.70 (0.19) | 1.20 (0.11) |
| Heart | 0.29 (0.08) | 0.93 (0.08) |
| Lungs | 0.66 (0.22) | 2.03 (0.16) |
| Kidneys | 0.46 (0.09) | 0.91 (0.08) |
| Intestine | 0.15 (0.04) | 0.48 (0.04) |
| Muscle | 0.17 (0.08) | 0.38 (0.04) |
| Bone | 0.19 (0.06) | 0.58 (0.06) |
| Skin | 0.42 (0.14) | 1.23 (0.12) |
| Tumor | 9.43 (2.53) | 23.18 (2.48) |
| . | PBS 120 h (n = 8), average (SD) . | STI571 120 h (n = 11), average (SD) . |
|---|---|---|
| Blood | 1.38 (0.42) | 4.45 (0.34) |
| Liver | 0.79 (0.26) | 1.58 (0.14) |
| Spleen | 0.70 (0.19) | 1.20 (0.11) |
| Heart | 0.29 (0.08) | 0.93 (0.08) |
| Lungs | 0.66 (0.22) | 2.03 (0.16) |
| Kidneys | 0.46 (0.09) | 0.91 (0.08) |
| Intestine | 0.15 (0.04) | 0.48 (0.04) |
| Muscle | 0.17 (0.08) | 0.38 (0.04) |
| Bone | 0.19 (0.06) | 0.58 (0.06) |
| Skin | 0.42 (0.14) | 1.23 (0.12) |
| Tumor | 9.43 (2.53) | 23.18 (2.48) |