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Table 3

Risk of pancreatic cancer (PC) among members of familial pancreatic cancer (FPC) kindreds stratified by their number of first-degree relatives (FDRs) with pancreatic cancer

No. of FDRs with PCaNo. of individualsPerson-years of follow-upObserved casesExpected casesbSIRc (95% CI)
3 or more 106 287.2 0.156 32.0 (10.4–74.7) 
634 1597.9 0.623 6.4 (1.8–16.4) 
1253 3388.0 0.442 4.5 (0.54–16.3) 
No. of FDRs with PCaNo. of individualsPerson-years of follow-upObserved casesExpected casesbSIRc (95% CI)
3 or more 106 287.2 0.156 32.0 (10.4–74.7) 
634 1597.9 0.623 6.4 (1.8–16.4) 
1253 3388.0 0.442 4.5 (0.54–16.3) 
a

Denotes each individual’s number of FDRs with pancreatic cancer (i.e., the number of their parents, siblings, and children with pancreatic cancer).

b

Adjusted for age, sex, and race.

c

SIR, standardized incidence ratio; CI, confidence interval.

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