American Association for Cancer Research

Table 3

Risk of pancreatic cancer (PC) among members of familial pancreatic cancer (FPC) kindreds stratified by their number of first-degree relatives (FDRs) with pancreatic cancer

No. of FDRs with PC^a	No. of individuals	Person-years of follow-up	Observed cases	Expected cases^b	SIR^c (95% CI)
3 or more	106	287.2	5	0.156	32.0 (10.4–74.7)
2	634	1597.9	4	0.623	6.4 (1.8–16.4)
1	1253	3388.0	2	0.442	4.5 (0.54–16.3)

No. of FDRs with PC^a	No. of individuals	Person-years of follow-up	Observed cases	Expected cases^b	SIR^c (95% CI)
3 or more	106	287.2	5	0.156	32.0 (10.4–74.7)
2	634	1597.9	4	0.623	6.4 (1.8–16.4)
1	1253	3388.0	2	0.442	4.5 (0.54–16.3)

Denotes each individual’s number of FDRs with pancreatic cancer (i.e., the number of their parents, siblings, and children with pancreatic cancer).

Adjusted for age, sex, and race.

SIR, standardized incidence ratio; CI, confidence interval.

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