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Table 2

Summary of promoter region methylation status in normal and in ductal carcinoma in situ (DCIS) and invasive breast cancer tissue correlated with protein expressiona

UpstreamDownstreamExpression statusPrevalenceb
Normal U/Mc  
     
DCIS 5/8 
 2/8 
 − 1/8 
     
Invasive − 2/12 
 2/12 
 − 7/12 
 2/12 
UpstreamDownstreamExpression statusPrevalenceb
Normal U/Mc  
     
DCIS 5/8 
 2/8 
 − 1/8 
     
Invasive − 2/12 
 2/12 
 − 7/12 
 2/12 
a

The designation of a tumor as positive for methylation, M, means a distinct band for the methylated MSP product was observed as shown in figure 4.

b

Prevalence for composite changes (number of samples demonstrating specified characteristics/total number of samples).

c

U, unmethylated; M, methylated.

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