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Table 1

Growth of cyclic AMP-responsive element binding (CREB)-transfected cells in soft agar

BNL1ME cells stably transfected with plasmids expressing any one of the specified CREB variants (first column) were sowed into soft agar. Pictures of the colonies were taken under microscope (magnification, ×200); a typical colony is presented, the size was measured and the volume of the colony was determined. The volume of an average colony is presented. The numbers of colonies in each plate were counted, and the percentage of colony forming cells was calculated relative to the number of sowed cells. The results represent an average from several experiments; the SD and Pcompared with wild type are indicated.

   
   
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