Mutations of PTPN11 in human cancer
| Tumor type . | No. of cases . | Exon . | Mutations . |
|---|---|---|---|
| Lung adenocarcinoma (1) | 118 | 3 | E76V |
| Lung cancer cell lines (2) | 65 | 2 | V45L |
| 3 | N58S | ||
| Colon cancer (1) | 196 | 3 | E76G |
| AML (4) | 65 | 3 | D61Y |
| 3 | E69V | ||
| 8 | R289G | ||
| 13 | G503V | ||
| Neuroblastoma (3) | 89 | 3 | Y62C |
| 3 | E69K | ||
| 13 | T507K | ||
| Melanoma (1) | 10 | 4 | R138Q |
| Tumor type . | No. of cases . | Exon . | Mutations . |
|---|---|---|---|
| Lung adenocarcinoma (1) | 118 | 3 | E76V |
| Lung cancer cell lines (2) | 65 | 2 | V45L |
| 3 | N58S | ||
| Colon cancer (1) | 196 | 3 | E76G |
| AML (4) | 65 | 3 | D61Y |
| 3 | E69V | ||
| 8 | R289G | ||
| 13 | G503V | ||
| Neuroblastoma (3) | 89 | 3 | Y62C |
| 3 | E69K | ||
| 13 | T507K | ||
| Melanoma (1) | 10 | 4 | R138Q |
NOTE. New mutations are shown in bold. The total number of mutations is indicated in parentheses.